The interplay between pathogens and Atg8 family proteins: thousand-faced interactions.
Sign Up to like & getrecommendations! Published in 2021 at "FEBS open bio"
DOI: 10.1002/2211-5463.13318
Abstract: Autophagy is an intracellular degradation and recycling process that can also remove pathogenic intracellular bacteria and viruses from within cells (referred to as xenophagy) and activate the adaptive immune responses. But autophagy - especially Atg… read more here.
Keywords: atg8 family; interplay pathogens; family; pathogens atg8 ... See more keywords
Bro1 family proteins harmonize cargo sorting with vesicle formation
Sign Up to like & getrecommendations! Published in 2022 at "BioEssays"
DOI: 10.1002/bies.202100276
Abstract: The Endosomal Sorting Complexes Required for Transport (ESCRTs) drive membrane remodeling in a variety of cellular processes that include the formation of endosomal intralumenal vesicles (ILVs) during multivesicular body (MVB) biogenesis. During MVB sorting, ESCRTs… read more here.
Keywords: cargo; proteins harmonize; harmonize cargo; formation ... See more keywords
Apoptotic mitochondrial poration by a growing list of pore‐forming BCL‐2 family proteins
Sign Up to like & getrecommendations! Published in 2023 at "BioEssays"
DOI: 10.1002/bies.202200221
Abstract: The pore‐forming BCL‐2 family proteins are effectors of mitochondrial poration in apoptosis initiation. Two atypical effectors—BOK and truncated BID (tBID)—join the canonical effectors BAK and BAX. Gene knockout revealed developmental phenotypes in the absence the… read more here.
Keywords: bcl family; pore forming; mitochondrial poration; forming bcl ... See more keywords
The role of TRIM family proteins in autophagy, pyroptosis, and diabetes mellitus
Sign Up to like & getrecommendations! Published in 2021 at "Cell Biology International"
DOI: 10.1002/cbin.11550
Abstract: The ubiquitin‐proteasome system, which is one of the systems for cell protein homeostasis and degradation, happens through the ordered and coordinated action of three types of enzymes, E1 ubiquitin‐activating enzyme, E2 ubiquitin‐carrier enzyme, E3 ubiquitin‐protein… read more here.
Keywords: autophagy pyroptosis; diabetes mellitus; role; trim family ... See more keywords
Diversification of the calponin family proteins by gene amplification and repeat expansion of calponin‐like motifs
Sign Up to like & getrecommendations! Published in 2021 at "Cytoskeleton"
DOI: 10.1002/cm.21683
Abstract: The calponin family proteins in vertebrates, including calponin and transgelin (also known as SM22 or NP25), regulate actin‐myosin interaction and actin filament stability and are involved in regulation of muscle contractility and cell migration. Related… read more here.
Keywords: amplification repeat; calponin family; family proteins; gene amplification ... See more keywords
Vav family proteins constitute disparate branching points for distinct BCR signaling pathways
Sign Up to like & getrecommendations! Published in 2020 at "European Journal of Immunology"
DOI: 10.1002/eji.202048621
Abstract: Antigen recognition by B‐cell antigen receptors (BCRs) activates distinct intracellular signaling pathways that control the differentiation fate of activated B lymphocytes. BCR‐proximal signaling enzymes comprise protein tyrosine kinases, phosphatases, and plasma membrane lipid‐modifying enzymes, whose… read more here.
Keywords: signaling pathways; family; constitute disparate; proteins constitute ... See more keywords
Multiple functions of CALCOCO family proteins in selective autophagy
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30836
Abstract: Selective autophagy is the lysosomal degradation of specific intracellular components sequestered into autophagosomes, late endosomes, or lysosomes through the activity of selective autophagy receptors. CALCOCO family proteins are the newly found selective autophagy receptors, which… read more here.
Keywords: proteins selective; selective autophagy; family proteins; calcoco family ... See more keywords
When RING finger family proteins meet SARS‐CoV‐2
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Virology"
DOI: 10.1002/jmv.27701
Abstract: The pandemic coronavirus disease 2019 (COVID‐19), caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), is currently the most formidable challenge to humankind. Understanding the complicated virus‐host interplay is crucial for fighting against viral infection.… read more here.
Keywords: ring finger; finger family; proteins meet; rnf proteins ... See more keywords
Reconstitution and Characterization of BCL-2 Family Proteins in Lipid Bilayer Nanodiscs.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8861-7_16
Abstract: The BCL-2 family proteins are key regulators of programmed cell death or apoptosis, and represent important targets for the development of anticancer drugs. Because their functions are intimately connected with intracellular membranes, it is important… read more here.
Keywords: bilayer nanodiscs; bcl family; family; lipid bilayer ... See more keywords
Zic Family Proteins in Emerging Biomedical Studies.
Sign Up to like & getrecommendations! Published in 2018 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-981-10-7311-3_12
Abstract: Zic family proteins have been investigated in various biomedical studies. Here we summarize the contact points between Zic proteins and recent medical research. The topics cover a wide range, reflecting the pleiotropic roles of these… read more here.
Keywords: medicine; biomedical studies; family proteins; zic family ... See more keywords
BAG family proteins contributes to autophagy-mediated multidrug resistance of tumor
Sign Up to like & getrecommendations! Published in 2022 at "Clinical and Translational Oncology"
DOI: 10.1007/s12094-022-02819-6
Abstract: Multidrug resistance (MDR) is a significant cause of tumor treatment failure. Accumulating evidence suggests that autophagy plays a significant role in the development of MDR. Autophagy is a conserved mechanism that maintains tumor homeostasis by… read more here.
Keywords: tumor; family proteins; multidrug resistance; bag family ... See more keywords