Diverse roles for the ror‐family receptor tyrosine kinases in neurons and glial cells during development and repair of the nervous system
Sign Up to like & getrecommendations! Published in 2018 at "Developmental Dynamics"
DOI: 10.1002/dvdy.24515
Abstract: The Ror‐family of receptor tyrosine kinases (RTKs) are involved critically in tissue genesis and organogenesis during development. In mammals, Ror1 and Ror2, members of the Ror‐family RTKs, have been shown to mediate cell polarity, migration,… read more here.
Keywords: family receptor; nervous system; ror family; family ... See more keywords
Small-Molecule Ligands as Potential GDNF Family Receptor Agonists
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DOI: 10.1021/acsomega.7b01932
Abstract: To find out potential GDNF family receptor α1 (GFRα1) agonists, small molecules were built up by molecular fragments according to the structure-based drug design approach. Molecular docking was used to identify their binding modes to… read more here.
Keywords: gdnf family; family receptor; potential gdnf; agonists small ... See more keywords
Abstract 1555: Monoclonal antibodies targeting the TAM family of receptor tyrosine kinases
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DOI: 10.1158/1538-7445.am2019-1555
Abstract: The TAM receptors (Tyro3/Axl/MerTK) family of receptor tyrosine kinases (RTKs) are important negative regulators of innate immunity. TAM receptor activation in myeloid cells by its ligands Gas6 or Protein S (PROS) promotes phosphatidylserine-dependent efferocytosis of… read more here.
Keywords: tam receptors; receptor tyrosine; tam; family receptor ... See more keywords