Family-wide Analysis of the Inhibition of Arf Guanine Nucleotide Exchange Factors with Small Molecules: Evidence of Unique Inhibitory Profiles.
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DOI: 10.1021/acs.biochem.7b00706
Abstract: Arf GTPases and their guanine nucleotide exchange factors (ArfGEFs) are major regulators of membrane traffic and organelle structure in cells. They are associated with a variety of diseases and are thus attractive therapeutic targets for… read more here.
Keywords: guanine nucleotide; nucleotide exchange; family wide; exchange factors ... See more keywords