No Evidence Indicates Famotidine Reduces the Risk of Serious Disease in COVID-19 Patients After Propensity Score Matching: Meta-Analysis and Systematic Reviews
Sign Up to like & getrecommendations! Published in 2021 at "Digestive Diseases and Sciences"
DOI: 10.1007/s10620-021-07214-9
Abstract: We read the article by Sun et al. published in Digestive Diseases and Sciences with great interest. It finds famotidine has no statistically significant difference in reducing the risk of serious disease in COVID19 patients… read more here.
Keywords: famotidine; score matching; disease; covid ... See more keywords
Association of histamine with hypertension-induced cardiac remodeling and reduction of hypertrophy with the histamine-2-receptor antagonist famotidine compared with the beta-blocker metoprolol
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DOI: 10.1038/s41440-018-0109-2
Abstract: The association of histamine with adverse cardiac remodeling in chronic pressure overload has not received much attention. A pilot study in spontaneously hypertensive rats (SHRs) indicated a reduction of left ventricular hypertrophy (LVH) with a… read more here.
Keywords: reduction; famotidine; metoprolol; histamine ... See more keywords
The in-vitro effect of famotidine on sars-cov-2 proteases and virus replication
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DOI: 10.1038/s41598-021-84782-w
Abstract: The lack of coronavirus-specific antiviral drugs has instigated multiple drug repurposing studies to redirect previously approved medicines for the treatment of SARS-CoV-2, the coronavirus behind the ongoing COVID-19 pandemic. A recent, large-scale, retrospective clinical study… read more here.
Keywords: famotidine; proteases virus; effect famotidine; cov proteases ... See more keywords
Design of PEG-grafted-PLA nanoparticles as oral permeability enhancer for P-gp substrate drug model Famotidine
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DOI: 10.1080/02652048.2017.1290155
Abstract: Abstract Bioavailability of oral drugs can be limited by an intestinal excretion process mediated by P-glycoprotein (P-gp). Polyethylene glycol (PEG) is a known P-gp inhibitor. Dispersion of Famotidine (a P-gp substrate) within PEGylated nanoparticles (NPs)… read more here.
Keywords: design peg; nps prepared; famotidine; permeability ... See more keywords
Hydrodynamically Balanced Capsule of Famotidine: An Improved Delivery via Gastroretentive Hydrogels
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DOI: 10.52711/0974-360x.2021.00795
Abstract: Objective: The aim of the present study was to increase the absolute bioavailability of famotidine, enhanced patient compliance in the treatment of peptic ulcer by increasing its gastric residence time and controlled local release of… read more here.
Keywords: hydrodynamically balanced; famotidine; delivery; drug ... See more keywords