And-1 coordinates with the FANCM complex to regulate Fanconi Anemia signaling and cisplatin resistance.
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DOI: 10.1158/0008-5472.can-22-0769
Abstract: The Fanconi anemia (FA) pathway is essential for repairing DNA inter-strand crosslinks (ICL). ICLs induce stalled DNA replication forks and trigger activation of the FA pathway by promoting recruitment of the FANCM/FAAP24/MHF complex to ICL… read more here.
Keywords: fancm faap24; fanconi anemia; icl; cisplatin resistance ... See more keywords