FAP-Targeted Radionuclide Therapy of Advanced Radioiodine-Refractory Differentiated Thyroid Cancer With Multiple Cycles of 177Lu-FAPI-46.
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DOI: 10.1097/rlu.0000000000004260
Abstract: ABSTRACT Many recent studies began to explore the therapeutic potential of FAP-targeted radionuclide therapy for refractory cancers. In this case, we presented the experience of multiple cycles of 177Lu-FAPI-46 radionuclide therapy in a 34-year-old man… read more here.
Keywords: fap targeted; refractory; radionuclide therapy; 177lu fapi ... See more keywords
Abstract 1988: FAP-targeted non-internalising drug conjugates: A comparative evaluation between small molecules, antibodies and peptides
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DOI: 10.1158/1538-7445.am2023-1988
Abstract: Conventional cancer chemotherapy relies on the use of cytotoxic drugs which are not designed and capable of selective accumulation to neoplastic lesions. The conjugation to tumour-targeting delivery vehicles has been proposed as a strategy to… read more here.
Keywords: fap targeted; comparative evaluation; drug conjugates; drug ... See more keywords
Abstract 2810: Increasing the efficacy of KRASG12Cinhibitor therapy through the adjuvant use of FAP targeted radiotherapy in a murine model of lung cancer
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DOI: 10.1158/1538-7445.am2023-2810
Abstract: The purpose of this study was to evaluate the combined effects of KRAS targeted therapy and FAP targeted radiotherapy compared to either therapy alone in an animal model of lung cancer. KRAS is a protein… read more here.
Keywords: targeted radiotherapy; lung cancer; fap targeted; therapy ... See more keywords
Radioligands Targeting Fibroblast Activation Protein (FAP)
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DOI: 10.3390/cancers13225744
Abstract: Simple Summary FAP-targeted radiotracers, recently introduced in cancer treatment, accumulate in Cancer-Associated Fibroblasts (CAFs). CAFs are present in tumor lesions but do not correspond to genuine cancer cells, although they behave in an abnormal and… read more here.
Keywords: medicine; nuclear medicine; fap targeted; fap ... See more keywords