Synthesis and Preclinical Evaluation of a Novel FAPI-04 Dimer for Cancer Theranostics.
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DOI: 10.1021/acs.molpharmaceut.2c00965
Abstract: Overexpression of fibroblast activation protein (FAP) in cancer-associated fibroblasts in a wide variety of tumors enables a highly selective targeting strategy using FAP inhibitors (FAPIs). Quinoline-based FAPIs labeled with radionuclides have been widely developed for… read more here.
Keywords: fapi; novel fapi; fapi dimer; 68ga fapi ... See more keywords