Engineered dynamic distribution of malonyl-CoA flux for improving polyketide biosynthesis in Komagataella phaffii.
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DOI: 10.1016/j.jbiotec.2020.06.012
Abstract: Malonyl-CoA is a basic but limited precursor for the biosynthesis of various bioactive compounds and life-supporting fatty acids in cells. This study develops a biosynthetic system to dynamically redirect malonyl-CoA flux and improve production of… read more here.
Keywords: fapo; prm1 fapr; coa; malonyl coa ... See more keywords