Articles with "farnesyl diphosphate" as a keyword



Structural Insights into the Substrate Binding of Farnesyl Diphosphate Synthase FPPS1 from Silkworm, Bombyx mori.

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Published in 2024 at "Journal of agricultural and food chemistry"

DOI: 10.1021/acs.jafc.3c06741

Abstract: Farnesyl diphosphate synthase (FPPS) is an important enzyme involved in the juvenile hormone (JH) biosynthesis pathway. Herein, we report the crystal structure of a type-I Lepidopteran FPPS from Bombyx mori (BmFPPS1) at 2.80 Å resolution.… read more here.

Keywords: substrate binding; bombyx mori; farnesyl diphosphate; diphosphate synthase ... See more keywords

Cyclo-farnesyl Diphosphate-Dependent Prenylation in Fungi.

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Published in 2024 at "Organic letters"

DOI: 10.1021/acs.orglett.4c03154

Abstract: A conserved two-gene cassette in fungi was discovered by genome mining, which encodes a UbiA family intramembrane prenyltansferase (VviA) and a haloacid dehalogenase-like hydrolase family terpene cyclase (VviB), respectively. A series of in vivo and… read more here.

Keywords: diphosphate; cyclo farnesyl; dependent prenylation; farnesyl diphosphate ... See more keywords

A cytosolic bifunctional geranyl/farnesyl diphosphate synthase provides MVA-derived GPP for geraniol biosynthesis in rose flowers.

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Published in 2023 at "Proceedings of the National Academy of Sciences of the United States of America"

DOI: 10.1073/pnas.2221440120

Abstract: Geraniol derived from essential oils of various plant species is widely used in the cosmetic and perfume industries. It is also an essential trait of the pleasant smell of rose flowers. In contrast to other… read more here.

Keywords: biosynthesis; geraniol; farnesyl diphosphate; rose flowers ... See more keywords

Functional characterization and transcriptional activity analysis of Dryopteris fragrans farnesyl diphosphate synthase genes

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Published in 2023 at "Frontiers in Plant Science"

DOI: 10.3389/fpls.2023.1105240

Abstract: Farnesyl diphosphate synthase (FPS), a key enzyme of the terpene metabolic pathway, catalyzes the precursor of sesquiterpene compounds farnesyl diphosphate (FPP) synthesis, and plays an important role in regulating plant growth and development. Dryopteris fragrans… read more here.

Keywords: functional characterization; farnesyl diphosphate; transcriptional activity; activity ... See more keywords

Farnesyl diphosphate synthase promotes cell proliferation by regulating gene expression and alternative splicing profiles in HeLa cells

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Published in 2023 at "Oncology Letters"

DOI: 10.3892/ol.2023.13731

Abstract: Farnesyl diphosphate synthase (FDPS), an essential enzyme involved in the mevalonate pathway, is implicated in various diseases, including multiple types of cancer. As an RNA-binding protein (RBP), FDPS is also involved in transcriptional and post-transcriptional… read more here.

Keywords: cell proliferation; hela cells; proliferation; fdps ... See more keywords