The farnesyltransferase β‐subunit RAM1 regulates localization of RAS proteins and appressorium‐mediated infection in Magnaporthe oryzae
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Plant Pathology"
DOI: 10.1111/mpp.12838
Abstract: Summary Post‐translational farnesylation can regulate subcellular localization and protein–protein interaction in eukaryotes. The function of farnesylation is not well identified in plant pathogenic fungi, particularly during the process of fungal infection. Here, through functional analyses… read more here.
Keywords: ram1; appressorium; farnesyltransferase; infection ... See more keywords
Protein farnesylation is upregulated in Alzheimer’s human brains and neuron-specific suppression of farnesyltransferase mitigates pathogenic processes in Alzheimer’s model mice
Sign Up to like & getrecommendations! Published in 2021 at "Acta Neuropathologica Communications"
DOI: 10.1186/s40478-021-01231-5
Abstract: The pathogenic mechanisms underlying the development of Alzheimer’s disease (AD) remain elusive and to date there are no effective prevention or treatment for AD. Farnesyltransferase (FT) catalyzes a key posttranslational modification process called farnesylation, in… read more here.
Keywords: farnesyltransferase; protein farnesylation; human brains; mice ... See more keywords