Lipid Nanoparticle Delivery of Fas Plasmid Restores Fas Expression to Suppress Melanoma Growth In Vivo.
Sign Up to like & getrecommendations! Published in 2022 at "ACS nano"
DOI: 10.1021/acsnano.2c04420
Abstract: Fas ligand (FasL), expressed on the surface of activated cytotoxic T lymphocytes (CTLs), is the physiological ligand for the cell surface death receptor, Fas. The Fas-FasL engagement initiates diverse signaling pathways, including the extrinsic cell… read more here.
Keywords: fas expression; cell; melanoma; tumor cells ... See more keywords
Regulation of fibroblast Fas expression by soluble and mechanical pro-fibrotic stimuli
Sign Up to like & getrecommendations! Published in 2018 at "Respiratory Research"
DOI: 10.1186/s12931-018-0801-4
Abstract: BackgroundFibroblast apoptosis is a critical component of normal repair and the acquisition of an apoptosis-resistant phenotype contributes to the pathogenesis of fibrotic repair. Fibroblasts from fibrotic lungs of humans and mice demonstrate resistance to apoptosis… read more here.
Keywords: fas expression; apoptosis; fibroblast fas; expression ... See more keywords
Fas expression is downregulated in gastric cancer
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Medicine Reports"
DOI: 10.3892/mmr.2016.6037
Abstract: The aim of the present study was to investigate Fas expression in tumor samples from patients with gastric cancer, in order to determine the involvement of the Fas signaling pathway. The protein expression levels of… read more here.
Keywords: gastric cancer; fas expression; caspase caspase; expression ... See more keywords
Pterostilbene increases Fas expression in T-lymphoblastic leukemia cell lines
Sign Up to like & getrecommendations! Published in 2019 at "Research in Pharmaceutical Sciences"
DOI: 10.4103/1735-5362.251853
Abstract: Treatment of acute lymphoblastic leukemia (ALL) has been promising in last decades, but side effects still persist and searching for the least toxic agents continue. Pterostilbene (PTE) is a natural compound with several anti-cancer and… read more here.
Keywords: cell lines; cell; fas expression; lymphoblastic leukemia ... See more keywords