Fas (CD95)/FasL (CD178) system during ageing.
Sign Up to like & getrecommendations! Published in 2023 at "Cell biology international"
DOI: 10.1002/cbin.12032
Abstract: The Fas/FasL system plays a central role in the physiological regulation of apoptosis and has been implicated in the pathogenesis of several neoplasms and diseases of the immune system. Until now, it has received little… read more here.
Keywords: system; fas cd95; fasl; fasl system ... See more keywords
Genome‐wide RNA‐Seq identifies Fas/FasL‐mediated tumoricidal activity of embryonic stem cells
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Cancer"
DOI: 10.1002/ijc.31201
Abstract: The discovery of tumor tropism of stem cells revealed the intimate relationship between stem cells and tumor cells, but the functional role of stem cells in tumorigenesis is poorly understood. To investigate embryonic stem cell… read more here.
Keywords: cell; tumor cells; fas fasl; stem ... See more keywords
Stimulation of Fas/FasL‐mediated apoptosis by luteolin through enhancement of histone H3 acetylation and c‐Jun activation in HL‐60 leukemia cells
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.22807
Abstract: Luteolin (3′,4′,5,7‐tetrahydroxyflavone), which exists in fruits, vegetables, and medicinal herbs, is used in Chinese traditional medicine for treating various diseases, such as hypertension, inflammatory disorders, and cancer. However, the gene‐regulatory role of luteolin in cancer… read more here.
Keywords: histone acetylation; acetylation; jun; fas fasl ... See more keywords
Mechanism of 2,4‐Dichlorophenoxyacetic acid‐induced damage to rat testis via Fas/FasL pathway and the protective effect of Lycium barbarum polysaccharides
Sign Up to like & getrecommendations! Published in 2022 at "Environmental Toxicology"
DOI: 10.1002/tox.23635
Abstract: The herbicide 2,4‐Dichlorophenoxyacetic acid (2,4‐D) is widely used to control broadleaved weeds and has been associated with male infertility. We studied the molecular mechanisms of 2,4‐D induced male reproductive system damage and the protective effects… read more here.
Keywords: dichlorophenoxyacetic acid; lycium barbarum; fas fasl; barbarum polysaccharides ... See more keywords
Lead induces apoptosis in mouse TM3 Leydig cells through the Fas/FasL death receptor pathway.
Sign Up to like & getrecommendations! Published in 2017 at "Environmental toxicology and pharmacology"
DOI: 10.1016/j.etap.2017.08.034
Abstract: The study was aimed to investigate the effect of Pb toxicity on mouse Leydig cells and its molecular mechanism. The TM3 cells were cultured in vitro and exposed to Pb at different concentrations for 24h.… read more here.
Keywords: apoptosis; death receptor; fas fasl; fasl death ... See more keywords
Passive smoking induces rat testicular injury via the FAS/FASL pathway.
Sign Up to like & getrecommendations! Published in 2019 at "Drug and chemical toxicology"
DOI: 10.1080/01480545.2019.1659807
Abstract: The mechanisms by which cigarette smoke (CS) exposure has a detrimental effect on the male reproductive system is still not fully understood. We aimed to elucidate the role of cigarette smoke-induced injury by the Fas/FasL… read more here.
Keywords: fasl pathway; exposure; smoking; fas fasl ... See more keywords
The role of the Fas/FasL signaling pathway in environmental toxicant-induced testicular cell apoptosis: An update
Sign Up to like & getrecommendations! Published in 2018 at "Systems Biology in Reproductive Medicine"
DOI: 10.1080/19396368.2017.1422046
Abstract: ABSTRACT The Fas/FasL signaling pathway is one of the major pathways that regulate apoptosis. Increasing studies have shown that the activation of the Fas/FasL signaling pathway is closely associated with testicular cell apoptosis. However, the… read more here.
Keywords: death; fasl signaling; fas fasl; factor ... See more keywords
Quantitative assessment of the relationship between Fas/FasL genes polymorphisms and head and neck cancer risk
Sign Up to like & getrecommendations! Published in 2018 at "Medicine"
DOI: 10.1097/md.0000000000009873
Abstract: Background: Molecular epidemiological studies have demonstrated a closer association between Fas/FasL polymorphisms and head and neck cancer (HNC) risk, and the results of these published studies were inconsistent. We therefore performed this meta-analysis to explore… read more here.
Keywords: polymorphisms head; risk; hnc risk; fas fasl ... See more keywords
Doxorubicin‐induces NFAT/Fas/FasL cardiac apoptosis in rats through activation of calcineurin and P38 MAPK and inhibition of mTOR signalling pathways
Sign Up to like & getrecommendations! Published in 2019 at "Clinical and Experimental Pharmacology and Physiology"
DOI: 10.1111/1440-1681.13225
Abstract: This study investigated the role of NFAT/Fas/FasL axis in cardiomyocyte apoptosis following doxorubicin (DOX) treatment in rats and evaluated the involvement and regulation of all NFAT members in cardiac apoptosis. Forty adult male Wistar rats… read more here.
Keywords: p38 mapk; nfat fas; inhibition; p38 ... See more keywords
Fas‐FasL interaction in cytotoxic T cell‐mediated vitiligo: The role of lesional expression of tumor necrosis factor‐α and interferon‐γ in Fas‐mediated melanocyte apoptosis
Sign Up to like & getrecommendations! Published in 2019 at "Experimental Dermatology"
DOI: 10.1111/exd.14053
Abstract: Vitiligo is an acquired skin depigmentation disorder resulting from the selective loss of epidermal melanocytes, and previous studies have suggested that a T lymphocyte‐mediated mechanism has a role in melanocyte loss. Although Fas‐Fas ligand (FasL)… read more here.
Keywords: apoptosis; fas fasl; expression; mediated apoptosis ... See more keywords
Effect of Fas/FasL signaling pathway activation in trophoblasts on recurrent spontaneous abortion
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Obstetrics and Gynaecology Research"
DOI: 10.1111/jog.14742
Abstract: To investigate the expression of Fas/FasL in human villous trophoblast cell HTR8‐S/Vneo of patients with recurrent spontaneous abortion (RSA), and to explore the related function and molecular mechanism of Fas/FasL signaling pathway. read more here.
Keywords: recurrent spontaneous; spontaneous abortion; fasl signaling; signaling pathway ... See more keywords