Fas‐FasL interaction in cytotoxic T cell‐mediated vitiligo: The role of lesional expression of tumor necrosis factor‐α and interferon‐γ in Fas‐mediated melanocyte apoptosis
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DOI: 10.1111/exd.14053
Abstract: Vitiligo is an acquired skin depigmentation disorder resulting from the selective loss of epidermal melanocytes, and previous studies have suggested that a T lymphocyte‐mediated mechanism has a role in melanocyte loss. Although Fas‐Fas ligand (FasL)… read more here.
Keywords: apoptosis; fas fasl; expression; mediated apoptosis ... See more keywords
Hepatitis B Spliced Protein (HBSP) Suppresses Fas-Mediated Hepatocyte Apoptosis via Activation of PI3K/Akt Signaling
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DOI: 10.1128/jvi.01273-18
Abstract: Our study revealed a previously unappreciated role of HBSP in Fas-mediated apoptosis. The antiapoptotic activity of HBSP is important for understanding hepatitis B virus pathogenesis. In particular, HBV variants associated with hepatoma carcinoma may downregulate… read more here.
Keywords: apoptosis; hepatitis; hbsp; activity ... See more keywords
Abstract 2348: BRD4 regulates the expression of Livin and thereby confers resistance to Fas-mediated immune cytotoxicity in aggressive B-cell lymphoma
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DOI: 10.1158/1538-7445.sabcs18-2348
Abstract: Aggressive types of non-Hodgkin’s lymphoma (NHL) include Burkitt’s lymphoma (BL) and diffuse large B-cell lymphoma (DLBCL), which are germinal center (GC) B-derived lymphomas. The death receptor Fas is expressed in GC B-lymphocytes and contributes to… read more here.
Keywords: cell lymphoma; expression livin; fas mediated; lymphoma ... See more keywords