Anti-Metastasis Fascin Inhibitors Decrease the Growth of Specific Subtypes of Cancers
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DOI: 10.3390/cancers12082287
Abstract: Fascin is an actin-bundling protein that is critical for filopodial formation and other cellular cytoskeletal structures. An elevated expression of fascin has been observed in tumor cells and is correlated with a shorter survival of… read more here.
Keywords: metastasis; fascin; growth specific; inhibitors decrease ... See more keywords
Fascin Inhibitors Decrease Cell Migration and Adhesion While Increase Overall Survival of Mice Bearing Bladder Cancers
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DOI: 10.3390/cancers13112698
Abstract: Simple Summary Fascin is an actin-bundling protein, and is highly expressed in metastatic tumor cells. Small molecule fascin inhibitors have been recently developed to block tumor cell migration, invasion, and metastasis. Here we have tested… read more here.
Keywords: bladder cancer; bladder cancers; bladder; migration ... See more keywords