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Fascin1 empowers YAP mechanotransduction and promotes cholangiocarcinoma development

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Published in 2021 at "Communications Biology"

DOI: 10.1038/s42003-021-02286-9

Abstract: Mechanical forces control cell behavior, including cancer progression. Cells sense forces through actomyosin to activate YAP. However, the regulators of F-actin dynamics playing relevant roles during mechanostransduction in vitro and in vivo remain poorly characterized.… read more here.

Keywords: cholangiocarcinoma development; yap mechanotransduction; empowers yap; fascin1 empowers ... See more keywords