Combining the G‐protein‐coupled receptor 40 agonist fasiglifam with sitagliptin improves glycaemic control in patients with type 2 diabetes with or without metformin: A randomized, 12‐week trial
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DOI: 10.1111/dom.12921
Abstract: To evaluate the efficacy and safety of fasiglifam, an orally active G‐protein‐coupled receptor 40 agonist, in combination with the dipeptidyl peptidase‐4 inhibitor sitagliptin, in patients with type 2 diabetes inadequately controlled with diet/exercise (± metformin). read more here.
Keywords: patients type; receptor agonist; fasiglifam; protein coupled ... See more keywords
Enhanced chromatographic efficiency obtained with vacuum jacketed columns facilitates the rapid UHPLC/MS/MS-based analysis of fasiglifam in rat plasma.
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DOI: 10.2139/ssrn.4225414
Abstract: The use of vacuum jacketed LC columns (VJC) to minimize on- and post-column band broadening to maximize chromatographic performance has been evaluated as a potential route to improved high throughput (HT) analysis. Here the use… read more here.
Keywords: rat plasma; jacketed columns; analysis; fasiglifam ... See more keywords