Fatty acid synthase as a potential new therapeutic target for cervical cancer.
Sign Up to like & getrecommendations! Published in 2022 at "Anais da Academia Brasileira de Ciencias"
DOI: 10.1590/0001-3765202220210670
Abstract: Fatty acid synthase (FASN) is the rate-limiting enzyme for the de novo synthesis of fatty acids in the cytoplasm of tumour cells. Many tumour cells express high levels of FASN, and its expression is associated… read more here.
Keywords: cervical cancer; acid synthase; fasn expression; fatty acid ... See more keywords
Prognostic and clinicopathological significance of fatty acid synthase in breast cancer: A systematic review and meta-analysis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2023.1153076
Abstract: Background Aberrant expression of fatty acid synthase (FASN) was demonstrated in various tumors including breast cancer. A meta-analysis was conducted to investigate the role of FASN in breast cancer development and its potential prognostic significance.… read more here.
Keywords: breast cancer; fasn expression; analysis; expression ... See more keywords
Fatty acid synthetase expression in triple-negative breast cancer
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Pathology and Translational Medicine"
DOI: 10.4132/jptm.2021.10.27
Abstract: Background Triple-negative breast cancer (TNBC) has a relatively poor prognosis. Research has identified potential metabolic targets, including fatty acid metabolism, in TNBC. The absence of effective target therapies for TNBC led to exploration of the… read more here.
Keywords: triple negative; expression; fasn expression; fasn ... See more keywords
AZGP1 suppresses the process of colorectal cancer after upregulating FASN expression via mTOR signal pathway.
Sign Up to like & getrecommendations! Published in 2020 at "General physiology and biophysics"
DOI: 10.4149/gpb_2019061
Abstract: Colorectal cancer (CRC) is the most common malignant gastrointestinal tumor. Obesity has been confirmed to be closely related to the occurrence of CRC, but the specific mechanism is not clear. This study mainly explored the… read more here.
Keywords: fasn expression; azgp1; pathway; expression ... See more keywords