Articles with "fast dissolving" as a keyword



The efficacy of oral piroxicam fast-dissolving tablets versus sublingual fentanyl in incident breakthrough pain due to bone metastases: a double-blinded randomized study

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Published in 2018 at "Supportive Care in Cancer"

DOI: 10.1007/s00520-018-4469-6

Abstract: PurposeBreakthrough pain (BTP) is a transient exacerbation of pain occurring in a patient with chronic, persistent pain. The most common type is incident pain that is mostly related to bone metastases. The oral mucosa is… read more here.

Keywords: fast dissolving; piroxicam fast; sublingual fentanyl; oral piroxicam ... See more keywords

Tip‐loaded fast‐dissolving microneedle patches for photodynamic therapy of subcutaneous tumor

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Published in 2018 at "Journal of Controlled Release"

DOI: 10.1016/j.jconrel.2018.07.038

Abstract: ABSTRACT 5‐Aminolevulinic acid (ALA) based photodynamic therapy (PDT) is a modality for the treatment of cancers. However, due to its hydrophilicity and zwitterionic nature, the transdermal delivery of ALA is limited for the PDT of… read more here.

Keywords: ala; fast dissolving; subcutaneous tumor; loaded fast ... See more keywords

Development of a fast dissolving sublingual film containing meloxicam nanocrystals for enhanced dissolution and earlier absorption

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Published in 2018 at "Journal of Drug Delivery Science and Technology"

DOI: 10.1016/j.jddst.2017.10.020

Abstract: Abstract The objective of this work was to prepare and evaluate fast dissolving sublingual films containing meloxicam nanocrystals (MLX-NS-FDSFs). Nanocrystals (NS) were utilized to allow for improved dissolution of the drug, whereas the films were… read more here.

Keywords: meloxicam nanocrystals; fast dissolving; dissolving sublingual; mlx fdsfs ... See more keywords

The Application of 3D Printing in the Formulation of Multilayered Fast Dissolving Oral Films.

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Published in 2018 at "Journal of pharmaceutical sciences"

DOI: 10.1016/j.xphs.2017.11.019

Abstract: Fast-dissolving oral films (FDFs) provide an alternative approach to increase consumer acceptance by advantage of rapid dissolution and administration without water. Usually, FDFs require taste-masking agents. However, inclusion of these excipients could make developing the… read more here.

Keywords: slfdfs; fast dissolving; oral films; formulation ... See more keywords

Griffithsin carrageenan fast dissolving inserts prevent SHIV HSV-2 and HPV infections in vivo

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Published in 2018 at "Nature Communications"

DOI: 10.1038/s41467-018-06349-0

Abstract: Human immunodeficiency virus (HIV) pre-exposure prophylaxis (PrEP) strategies with proven in vivo efficacy rely on antiretroviral drugs, creating the potential for drug resistance and complicated treatment options in individuals who become infected. Moreover, on-demand products… read more here.

Keywords: grft; fast dissolving; carrageenan fast; hsv hpv ... See more keywords

Polymeric Oral Fast Dissolving Films of Metformin: Fabrication, Optimization, In Vitro and In Vivo Evaluation.

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Published in 2025 at "Drug development and industrial pharmacy"

DOI: 10.1080/03639045.2025.2592675

Abstract: BACKGROUND Metformin is gold standard for polycystic ovary syndrome (PCOS), but associated with gastrointestinal side effects, leading to poor patient adherence. Present oral fast-dissolving films (OFDFs) offer rapid disintegration, improving drug delivery, therapeutic outcomes, and… read more here.

Keywords: disintegration; drug; dissolving films; fast dissolving ... See more keywords

Central Composite Designed Fast Dissolving Tablets for Improved Solubility of the Loaded Drug Ondansetron Hydrochloride

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Published in 2022 at "BioMed Research International"

DOI: 10.1155/2022/2467574

Abstract: Ondansetron tablets that are directly compressed using crospovidone and croscarmellose as a synthetic super disintegrant are the subject of this investigation. A central composite, response surface, randomly quadratic, nonblock (version 13.0.9.0) 32 factorial design is… read more here.

Keywords: fast dissolving; composite designed; ondansetron hydrochloride; central composite ... See more keywords

Fabrication of polyvinyl alcohol based fast dissolving oral strips of sumatriptan succinate and metoclopramide HCL

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Published in 2020 at "Science Progress"

DOI: 10.1177/0036850420964302

Abstract: Migraine is a throbbing condition, usually associated with nausea and vomiting and requires concurrent administration of anti-migraine along with anti-emetic therapy. The current study was undertaken with an aim to fabricate fast dissolving oral strips… read more here.

Keywords: fast dissolving; metoclopramide hcl; oral strips; dissolving oral ... See more keywords

Formulation, Characterization, and Optimization of Captopril Fast-Dissolving Oral Films

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Published in 2018 at "AAPS PharmSciTech"

DOI: 10.1208/s12249-018-1027-y

Abstract: This work aimed to using optimization study to formulate a patient-friendly captopril fast-dissolving oral film with satisfactory disintegration time. Films were made with pullulan and hydroxypropyl methyl cellulose (HPMC) by using the solvent-casting method. Cellulose… read more here.

Keywords: fast dissolving; captopril fast; oral films; formulation ... See more keywords

Nanosuspension-Based Repaglinide Fast-Dissolving Buccal Film for Dissolution Enhancement

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Published in 2024 at "AAPS PharmSciTech"

DOI: 10.1208/s12249-024-02868-w

Abstract: Drug solubility and dissolution remain a significant challenge in pharmaceutical formulations. This study aimed to formulate and evaluate repanglinide (RPG) nanosuspension-based buccal fast-dissolving films (BDFs) for dissolution enhancement. RPG nanosuspension was prepared by the antisolvent-precipitation… read more here.

Keywords: nanosuspension based; dissolution; nanosuspension; rpg ... See more keywords

Fast-Dissolving Pullulan Film as a Solid Dosage Form for Sublingual Administration of Nifedipine-Loaded Nanocapsules

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Published in 2025 at "AAPS PharmSciTech"

DOI: 10.1208/s12249-025-03197-2

Abstract: Fast-dissolving pullulan films were developed as a final dosage form for the sublingual administration of nanocapsules containing nifedipine (NIFE). Eudragit® RS100 nanocapsule suspensions presenting 1 mg/mL of NIFE, 150 nm in size, and positive zeta… read more here.

Keywords: form sublingual; dosage form; sublingual administration; dissolving pullulan ... See more keywords