Accurate Prediction of Amide Exchange in the Fast Limit Reveals Thrombin Allostery.
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DOI: 10.1016/j.bpj.2018.11.023
Abstract: Amide hydrogen/deuterium exchange mass spectrometry (HDXMS) of proteins has become extremely popular for identifying ligand-binding sites, protein-protein interactions, intrinsic disorder, and allosteric changes upon protein modification. Such phenomena are revealed when amide exchange is measured… read more here.
Keywords: prediction amide; amide exchange; exchange; fast limit ... See more keywords