Protein resonance assignment by solid-state NMR based on 1H-detected 13C double-quantum spectroscopy at fast MAS.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of biomolecular NMR"
DOI: 10.1007/s10858-021-00386-6
Abstract: Solid-state NMR spectroscopy is a powerful technique to study insoluble and non-crystalline proteins and protein complexes at atomic resolution. The development of proton (1H) detection at fast magic-angle spinning (MAS) has considerably increased the analytical… read more here.
Keywords: solid state; fast mas; assignment; state nmr ... See more keywords
Suppressing 1H Spin Diffusion in Fast MAS Proton Detected Heteronuclear Correlation Solid-State NMR Experiments.
Sign Up to like & getrecommendations! Published in 2019 at "Solid state nuclear magnetic resonance"
DOI: 10.1016/j.ssnmr.2019.101636
Abstract: Fast magic angle spinning (MAS) and indirect detection by high gyromagnetic ratio (γ) nuclei such as proton or fluorine are increasingly utilized to obtain 2D heteronuclear correlation (HETCOR) solid-state NMR spectra of spin-1/2 nuclei by… read more here.
Keywords: solid state; fast mas; nmr experiments; spin diffusion ... See more keywords
Crystal structure validation of verinurad via proton-detected ultra-fast MAS NMR and machine learning
Sign Up to like & getrecommendations! Published in 2024 at "Faraday Discussions"
DOI: 10.1039/d4fd00076e
Abstract: The recent development of ultra-fast magic-angle spinning (MAS) (>100 kHz) provides new opportunities for structural characterization in solids. Here, we use NMR crystallography to validate the structure of verinurad, a microcrystalline active pharmaceutical ingredient. To… read more here.
Keywords: proton; structure; machine learning; ultra fast ... See more keywords