2,3′,4,4′,5‐Pentachlorobiphenyl attenuated fast‐twitch fibers and fiber size of skeletal muscle via disturbing thyroid hormone signaling and mitochondrial dynamics
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.4330
Abstract: Polychlorinated biphenyls (PCBs) affect multiple organs, and some of the effects are mediated by interfering with thyroid hormone (TH) signaling that regulates physiological processes in mammals. It remains unclear how PCBs affect skeletal muscle (SM).… read more here.
Keywords: hormone signaling; muscle; pcb118; thyroid hormone ... See more keywords
A chronic high-fat diet does not exacerbate muscle atrophy in fast-twitch skeletal muscle of aged mice.
Sign Up to like & getrecommendations! Published in 2023 at "Experimental physiology"
DOI: 10.1113/ep091106
Abstract: NEW FINDINGS What is the central question of this study? Ageing leads to a loss of mass in skeletal muscle, but the effect of obesity on ageing-related muscle wasting is unclear. In this study, we… read more here.
Keywords: twitch skeletal; muscle; obesity; fast twitch ... See more keywords
Differential protective effects of Radix astragali, herbal medicine, on immobilization-induced atrophy of slow-twitch and fast-twitch muscles.
Sign Up to like & getrecommendations! Published in 2020 at "Biomedical research"
DOI: 10.2220/biomedres.41.139
Abstract: Radix astragali is a popular traditional herbal medicine that provides significant protection against tissue injury in various models of oxidative stress-related diseases. In this study, we aimed to investigate whether administration of Radix astragali prevented… read more here.
Keywords: radix astragali; medicine; fast twitch; immobilization ... See more keywords
Modeling and simulation of excitation- contraction coupling of fast-twitch skeletal muscle fibers
Sign Up to like & getrecommendations! Published in 2020 at "Technology and Health Care"
DOI: 10.3233/thc-209003
Abstract: BACKGROUND: The current excitation-contraction coupling model of fast-twitch skeletal muscle fibers cannot completely simulate the excitation-contraction process. OBJECTIVE: To solve this problem, this study proposes an excitation-contraction model of fast-twitch skeletal muscle fibers based on… read more here.
Keywords: excitation contraction; model; twitch skeletal; fast twitch ... See more keywords
LncRNA SMARCD3-OT1 Promotes Muscle Hypertrophy and Fast-Twitch Fiber Transformation via Enhancing SMARCD3X4 Expression
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23094510
Abstract: Long noncoding RNA (lncRNA) plays a crucial part in all kinds of life activities, especially in myogenesis. SMARCD3 (SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin, subfamily d, member 3) is a member of the SWI/SNF protein… read more here.
Keywords: fast twitch; expression; twitch fiber; smarcd3 ot1 ... See more keywords
Palmitic Acid Inhibits Myogenic Activity and Expression of Myosin Heavy Chain MHC IIb in Muscle Cells through Phosphorylation-Dependent MyoD Inactivation
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24065847
Abstract: Sarcopenia associated with aging and obesity is characterized by the atrophy of fast-twitch muscle fibers and an increase in intramuscular fat deposits. However, the mechanism of fast-twitch fiber-specific atrophy remains unclear. In this study, we… read more here.
Keywords: muscle; expression; activity; mhc iib ... See more keywords
Apocynin Attenuates Diabetes-Induced Skeletal Muscle Dysfunction by Mitigating ROS Generation and Boosting Antioxidant Defenses in Fast-Twitch and Slow-Twitch Muscles
Sign Up to like & getrecommendations! Published in 2022 at "Life"
DOI: 10.3390/life12050674
Abstract: In response to diabetes mellitus, skeletal muscle is negatively affected, as is evident by reduced contractile force production, increased muscle fatigability, and increased levels of oxidative stress biomarkers. Apocynin is a widely used NADPH oxidase… read more here.
Keywords: twitch; muscle; slow twitch; twitch slow ... See more keywords