Fed or fasted state for oral therapies in breast cancer treatment? A comprehensive review of clinical practice recommendations.
Sign Up to like & getrecommendations! Published in 2021 at "Cancer treatment reviews"
DOI: 10.1016/j.ctrv.2021.102281
Abstract: In the last decades several anti-cancer drugs have been developed to treat patients with breast cancer, many of them orally administered, with ongoing efforts to substitute parenteral drugs with oral therapy. The latter is attractive… read more here.
Keywords: treatment; fed fasted; breast cancer; fasted state ... See more keywords
Low dose caffeine as a salivary tracer for the determination of gastric water emptying in fed and fasted state: A MRI validation study
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Pharmaceutics and Biopharmaceutics"
DOI: 10.1016/j.ejpb.2018.03.011
Abstract: Graphical abstract Figure. No caption available. &NA; Improving our knowledge about human gastrointestinal physiology and its impact on oral drug delivery is crucial for the development of new therapies and effective drug delivery systems. The… read more here.
Keywords: caffeine; water; study; fasted state ... See more keywords
Comparative Assessment of Miniaturized Screening Approaches for Selection of Polymers for Amorphous Drug Stabilization.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of pharmaceutical sciences"
DOI: 10.1016/j.xphs.2017.11.006
Abstract: The present work highlights the use of miniaturized approaches to screen and prioritize development of solid dispersions that provide stabilization of the amorphous drug against crystallization and enhanced dissolution over the crystalline form. The approaches… read more here.
Keywords: stabilization; screening approaches; drug; fasted state ... See more keywords
Fed- and Fasted-State Performance of Pretomanid Amorphous Solid Dispersions Formulated with an Enteric Polymer.
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DOI: 10.1021/acs.molpharmaceut.3c00174
Abstract: Weakly acid polymers with pH-responsive solubility are being used with increasing frequency in amorphous solid dispersion (ASD) formulations of drugs with low aqueous solubility. However, drug release and crystallization in a pH environment where the… read more here.
Keywords: state; microscopy; fasted state; release ... See more keywords
Competing in the Ramadan fasted state: for spirituality, health and performance
Sign Up to like & getrecommendations! Published in 2022 at "British Journal of Sports Medicine"
DOI: 10.1136/bjsports-2021-105230
Abstract: All professional athletes require effective nutrition, hydration and sleep strategies to optimise physical and mental health during training and competition. This is an annual challenge for Muslim athletes during the holy month of Ramadan, when… read more here.
Keywords: health; fasted state; competing ramadan; ramadan fasted ... See more keywords
Abstract P1-10-14: Abemaciclib tablet formulation is bioequivalent to capsules
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DOI: 10.1158/1538-7445.sabcs17-p1-10-14
Abstract: Introduction: Abemaciclib is being developed for the treatment of cancer, including advanced and metastatic breast cancer. Tablet formulations, which are smaller than the capsules used in the pivotal MONARCH 1, 2 and 3 breast cancer… read more here.
Keywords: part; fasted state; cancer; bioequivalent capsules ... See more keywords
Contribution of High-Intensity Interval Exercise in the Fasted State to Fat Browning: Potential Roles of Lactate and β-hydroxybutyrate.
Sign Up to like & getrecommendations! Published in 2023 at "Medicine and science in sports and exercise"
DOI: 10.1249/mss.0000000000003136
Abstract: ABSTRACT Purpose Fat browning contributes to energy consumption and may have metabolic benefits against obesity; however, the potential roles of lactate and β-hydroxybutyrate (β-HB) in fat browning remain unclear. We investigated the roles of a… read more here.
Keywords: fat browning; exercise fasted; fasted state; intensity ... See more keywords
Effects of Low/Medium-Intensity Exercise on Fat Metabolism after a 6-h Fast
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Environmental Research and Public Health"
DOI: 10.3390/ijerph192315502
Abstract: The effects of fasting and different exercise intensities on lipid metabolism were investigated in 12 male students aged 19.9 ± 1.4 years, with maximal oxygen consumption (VO2max) of 50.33 ± 4.0 mL/kg/min, using a counterbalanced… read more here.
Keywords: metabolism; exercise; intensity exercise; fasted state ... See more keywords