FASTKD1 and FASTKD4 have opposite effects on expression of specific mitochondrial RNAs, depending upon their endonuclease-like RAP domain
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DOI: 10.1093/nar/gkx164
Abstract: Abstract FASTK family proteins have been identified as regulators of mitochondrial RNA homeostasis linked to mitochondrial diseases, but much remains unknown about these proteins. We show that CRISPR-mediated disruption of FASTKD1 increases ND3 mRNA level,… read more here.
Keywords: rap domain; nd5 cyb; fastkd1 fastkd4; fastkd4 ... See more keywords