Panax quinquefolium saponin Optimizes Energy Homeostasis by Modulating AMPK-Activated Metabolic Pathways in Hypoxia-Reperfusion Induced Cardiomyocytes
Sign Up to like & getrecommendations! Published in 2020 at "Chinese Journal of Integrative Medicine"
DOI: 10.1007/s11655-020-3194-4
Abstract: To investigate the effects and underlying mechanisms of Panax quinquefolium saponin (PQS) on energy deficiency in hypoxia-reperfusion (H/R) induced cardiomyocytes. The H/R injury involved hypoxia for 3 h and then reperfusion for 2 h. Cardiomyocytes… read more here.
Keywords: pqs; hypoxia reperfusion; fat cd36; energy ... See more keywords
P2 Fatty acid transporter1 (FAT/CD36) and guanine nucleotide-binding protein G(I) subunit ALPHA-2 (GALPHAI2) are novel substrates of the cell surface localised palmitoyl transferase DHHC5
Sign Up to like & getrecommendations! Published in 2018 at "Heart"
DOI: 10.1136/heartjnl-2018-bscr.7
Abstract: Palmitoylation is the reversible addition of a 16 carbon fatty acid group to cysteine residues on proteins. The forward reaction is catalysed by DHHC palmitoyl acyl transferase (PAT) enzymes and there are 23 human isoforms.… read more here.
Keywords: dhhc5; fatty acid; cd36; galphai2 ... See more keywords
The Implication of PGC-1α on Fatty Acid Transport across Plasma and Mitochondrial Membranes in the Insulin Sensitive Tissues
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DOI: 10.3389/fphys.2017.00923
Abstract: PGC-1α coactivator plays a decisive role in the maintenance of lipid balance via engagement in numerous metabolic processes (i.e., Krebs cycle, β-oxidation, oxidative phosphorylation and electron transport chain). It constitutes a link between fatty acids… read more here.
Keywords: fatty acid; transport; pgc fatty; implication pgc ... See more keywords
FABP4 Controls Fat Mass Expandability (Adipocyte Size and Number) through Inhibition of CD36/SR-B2 Signalling
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24021032
Abstract: Adipose tissue hypertrophy during obesity plays pleiotropic effects on health. Adipose tissue expandability depends on adipocyte size and number. In mature adipocytes, lipid accumulation as triglycerides into droplets is imbalanced by lipid uptake and lipolysis.… read more here.
Keywords: cd36; fat mass; adipocyte size; cd36 signalling ... See more keywords