Loss of EGFR contributes to high-fat diet-induced nonalcoholic fatty liver disease.
Sign Up to like & getrecommendations! Published in 2023 at "FEBS letters"
DOI: 10.1002/1873-3468.14636
Abstract: Using a murine model of high-fat diet (HFD)-induced non-alcoholic fatty liver disease (NAFLD), we found that the expression of the epidermal growth factor receptor (EGFR) significantly decreased in hepatocytes. In vitro, free fatty acid influx… read more here.
Keywords: fatty liver; high fat; egfr; liver disease ... See more keywords
Effects of high‐fat diet‐induced adipokines and cytokines on colorectal cancer development
Sign Up to like & getrecommendations! Published in 2019 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.12751
Abstract: Colorectal cancer (CRC) is the third most common tumor worldwide, and recent epidemiological studies have indicated that obesity contributes to the morbidity and mortality of CRC. Furthermore, obesity‐related adipokines have been shown to be closely… read more here.
Keywords: fat diet; diet induced; adipokines cytokines; induced adipokines ... See more keywords
The effects of high-fat diet and metformin on urinary metabolites in diabetes and pre-diabetes rat models.
Sign Up to like & getrecommendations! Published in 2020 at "Biotechnology and applied biochemistry"
DOI: 10.1002/bab.2021
Abstract: High-fat diet (HFD) interferes with the dietary plan of patients with type 2 diabetes mellitus (T2DM). However, many diabetes patients consume food with higher fat content for a better taste bud experience. In this study,… read more here.
Keywords: fat diet; pre diabetes; hfd; diabetes pre ... See more keywords
Combination of metformin and berberine represses the apoptosis of sebocytes in high‐fat diet‐induced diabetic hamsters and an insulin‐treated human cell line
Sign Up to like & getrecommendations! Published in 2020 at "Cell Biochemistry and Function"
DOI: 10.1002/cbf.3504
Abstract: Obesity and insulin resistance affect metabolic reactions, but their ensuing contributions to macrophage metabolism remain insufficiently understood. We investigated the contributions of berberine and metformin combination to the inhibition of sebocyte apoptosis in high‐fat diet‐induced… read more here.
Keywords: fat diet; combination; apoptosis; diabetic hamsters ... See more keywords
Elucidation of the changes occurring at the proteome level in ovaries of high‐fat diet‐induced obese rats
Sign Up to like & getrecommendations! Published in 2022 at "Cell Biochemistry and Function"
DOI: 10.1002/cbf.3693
Abstract: High‐fat diet‐induced obesity adversely affects the female reproductive system. The metabolic changes that the high‐fat diet causes on the ovaries have not been elucidated. Herein, to understand the molecular and cellular mechanisms underlying the effects… read more here.
Keywords: elucidation changes; proteins involved; high fat; diet induced ... See more keywords
Nicotinamide mononucleotide alters body composition and ameliorates metabolic disorders induced by a high‐fat diet
Sign Up to like & getrecommendations! Published in 2023 at "IUBMB Life"
DOI: 10.1002/iub.2707
Abstract: Obesity is caused by an imbalance between calorie intake and energy expenditure, leading to excessive adipose tissue accumulation. Nicotinamide adenine dinucleotide (NAD+) is an important molecule in energy and signal transduction, and NAD+ supplementation therapy… read more here.
Keywords: nicotinamide mononucleotide; body composition; high fat; obesity ... See more keywords
Response to: Obesity and Vitamin D Metabolism Modifications
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Bone and Mineral Research"
DOI: 10.1002/jbmr.3743
Abstract: We thank Landrier and colleagues for their thoughtful comments regarding our recent publication regarding the role of decreased expression of CYP2R1 as a basis for reduced circulating levels of 25(OH)D in obese mice. First, Landrier… read more here.
Keywords: fat diet; obese mice; obesity; mice ... See more keywords
The effects of boron‐supplemented diets on adipogenesis‐related gene expressions, anti‐inflammatory, and antioxidative response in high‐fat fed rats
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23257
Abstract: The fatty liver syndrome caused by nutritional factors is a common cause of hepatic dysfunction globally. This research was designed to study the shielding effect of boron in rats fed a diet having high fat.… read more here.
Keywords: fed rats; fat; fat fed; high fat ... See more keywords
Camellia nitidissima Chi flower extract alleviates obesity and related complications and modulates gut microbiota composition in rats with high-fat-diet-induced obesity.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.10471
Abstract: BACKGROUND The aim of this study was to investigate the potential anti-obesity effects of Camellia nitidissima Chi flower extract (Cnfe) by examining its effects in terms of the regulation of lipid levels and modulation of… read more here.
Keywords: fat diet; rats high; diet induced; high fat ... See more keywords
Docosahexaenoic acid-acylated astaxanthin monoester ameliorates chronic high-fat diet-induced autophagy dysfunction via ULK1 pathway in the hypothalamus of mice.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.12429
Abstract: BACKGROUND Dietary astaxanthin (AST) exhibits the ability to resist lipid accumulation and stimulate hepatic autophagy. Natural AST predominantly exists in more stable esterified forms. More importantly, in our previous study, docosahexaenoic acid-acylated AST monoester (AST-DHA)… read more here.
Keywords: docosahexaenoic acid; fat diet; acid acylated; dha ... See more keywords
Effect of Tea Catechins on Gut Microbiota in High Fat Diet-Induced Obese Mice.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.12476
Abstract: BACKGROUND Tea catechins have been shown to be beneficial for obesity alleviation, diabetic prevention, and metabolic syndrome amelioration. The purpose of the present work is to explore the underlying mechanism linking the intestinal microbiota and… read more here.
Keywords: effect; gut microbiota; high fat; tea ... See more keywords