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Published in 2022 at "Phytotherapy Research"
DOI: 10.1002/ptr.7343
Abstract: Gut microbiota plays a key role in the pathophysiology of type 2 diabetes mellitus (T2D). Mulberry leaf has a hypoglycemic effect, but the potential mechanism is not fully understood. This study aimed to explore the…
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Keywords:
water extract;
gut microbiota;
induced high;
high fat ... See more keywords
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Published in 2020 at "Calcified Tissue International"
DOI: 10.1007/s00223-020-00684-5
Abstract: Osteocalcin, known as a bone gla protein, is considered a regulator of energy metabolism and behavior in its undercarboxylated form (ucOC). Antiresorptive drugs, such as alendronate, reduce serum level of ucOC. The purpose of the…
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Keywords:
alendronate;
fructose diet;
group;
fat high ... See more keywords
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Published in 2019 at "Nutrition"
DOI: 10.1016/j.nut.2019.02.020
Abstract: OBJECTIVE Intermittent fasting (IF) is a nutritional intervention with significant metabolic effects on the liver that are not yet fully understood. The aim of this study was to investigate the effects of IF on body…
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Keywords:
mice;
fat high;
beneficial effects;
steatosis ... See more keywords
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Published in 2022 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.2c00186
Abstract: A high-fat, high-fructose diet (HFFD) impairs cognitive functions and increases susceptibility to neurodegenerative disorders. Irisin and heat shock protein 70 (HSP70) are well known for their role in neuroprotection. The possible neuroprotective effects of fenofibrate…
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Keywords:
irisin;
hffd;
high fructose;
high fat ... See more keywords
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Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-48973-w
Abstract: Precise molecular pathways involved in the progression of non-alcoholic steatohepatitis (NASH) remain to be elucidated. As Mallory–Denk bodies were occasionally observed in the enlarged hepatocytes in NASH model rat (SHRSP5/Dmcr) fed high-fat and high-cholesterol (HFC)…
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Keywords:
phosphorylated inositol;
kinase;
hfc diet;
high fat ... See more keywords
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Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-95117-0
Abstract: Although the mechanism of action of the antidiabetic drug metformin is still a matter of discussions, it is well accepted that the gut plays an important role. To gain more insights into the mechanisms occurring…
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Keywords:
hfs diet;
high sucrose;
fat high;
high fat ... See more keywords
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Published in 2018 at "Archives of Physiology and Biochemistry"
DOI: 10.1080/13813455.2018.1510968
Abstract: Abstract Background: Exercise intervention is strongly recommended to manage metabolic diseases. In this study, we investigate, whether HIIT and CET can induce hepatic miR-122 expression, NAFLD rats with diabetes. Methods: 40 Wistar rats divided into…
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Keywords:
hiit;
fat high;
high fat;
mir 122 ... See more keywords
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Published in 2023 at "Pharmaceutical Biology"
DOI: 10.1080/13880209.2023.2166086
Abstract: Abstract Context α-Mangosteen (α-MG) attenuates insulin resistance (IR). However, it is still unknown whether α-MG could alleviate hepatic manifestations in IR rats. Objective To investigate the effect of α-MG on alleviating hepatic manifestations in IR…
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Keywords:
insulin resistance;
hepatic manifestations;
high fat;
histopathology ... See more keywords
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Published in 2022 at "Gut Microbes"
DOI: 10.1080/19490976.2021.2022442
Abstract: ABSTRACT Diet can not only provide nutrition for intestinal microbiota, it can also remodel them. However, is unclear whether and how diet affects the spread of antibiotic resistance genes (ARGs) in the intestinal microbiota. Therefore,…
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Keywords:
high sugar;
intestinal microbiota;
microbiota;
sugar high ... See more keywords
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Published in 2022 at "Thyroid"
DOI: 10.1089/thy.2021.0604
Abstract: Background: Levothyroxine (LT4) sodium is a standard treatment for hypothyroidism. Its absorption and bioavailability when taken as a tablet have been shown to be significantly decreased with concomitant food ingestion. Therefore, LT4 formulations are recommended…
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Keywords:
bioavailability;
high calorie;
high fat;
solution ... See more keywords
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Published in 2017 at "Biology of Reproduction"
DOI: 10.1095/biolreprod.116.142786
Abstract: Abstract Obesity has been linked with a host of metabolic and reproductive disorders including polycystic ovary syndrome (PCOS). While a clear association exists between obesity and PCOS, the exact nature of this relationship remains unexplained.…
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Keywords:
polycystic ovary;
high sugar;
fat high;
high fat ... See more keywords