Fat‐1 transgenic mice rich in endogenous omega‐3 fatty acids are protected from lipopolysaccharide‐induced cardiac dysfunction
Sign Up to like & getrecommendations! Published in 2021 at "ESC Heart Failure"
DOI: 10.1002/ehf2.13262
Abstract: Cardiac malfunctions developing in result of sepsis are hard to treat so they eventually contribute to the increased mortality. Previous reports indicated for therapeutic potential of exogenous ω‐3 polyunsaturated fatty acids (PUFA) in sepsis, but… read more here.
Keywords: induced cardiac; mice rich; fatty acids; fat transgenic ... See more keywords
Effects of n-3PUFAs on autophagy and inflammation of hypothalamus and body weight in mice.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.05.084
Abstract: OBJECTIVE Fat-1 transgenic mice were used as a model to study the effect of endogenous n-3 polyunsaturated fatty acids (n-3PUFAs) on the body weight, inflammatory factors and autophagy proteins in hypothalamus to explore the mechanism… read more here.
Keywords: hypothalamus; fat transgenic; transgenic mice; mice ... See more keywords
Fat‐1 expression alleviates atherosclerosis in transgenic rabbits
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.17188
Abstract: Atherosclerosis is the main cause of cardiovascular diseases. The Fat‐1 gene can express the n‐3 fatty acid desaturase, which converts n‐6 polyunsaturated fatty acids (PUFA) to n‐3 PUFAs. The role of n‐3 PUFAs in atherosclerosis… read more here.
Keywords: fat expression; expression alleviates; atherosclerosis; fat transgenic ... See more keywords
Sex-Specific Differences in Resolution of Airway Inflammation in Fat-1 Transgenic Mice Following Repetitive Agricultural Dust Exposure
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2021.785193
Abstract: In agriculture industries, workers are at increased risk for developing pulmonary diseases due to inhalation of agricultural dusts, particularly when working in enclosed confinement facilities. Agricultural dusts inhalation leads to unresolved airway inflammation that precedes… read more here.
Keywords: transgenic mice; fat transgenic; dust; dust exposure ... See more keywords