Biology of macrophage fate decision: Implication in inflammatory disorders
Sign Up to like & getrecommendations! Published in 2022 at "Cell Biology International"
DOI: 10.1002/cbin.11854
Abstract: The activation of immune cells in response to stimuli present in their microenvironment is regulated by their metabolic profile. Unlike the signal transduction events, which overlap to a huge degree in diverse cellular processes, the… read more here.
Keywords: fate decision; macrophage fate; decision implication; macrophage ... See more keywords
Modeling ncRNA-Mediated Circuits in Cell Fate Decision.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8982-9_16
Abstract: Noncoding RNAs (ncRNAs) play critical roles in essential cell fate decisions. However, the exact molecular mechanisms underlying ncRNA-mediated bistable switches remain elusive and controversial. In recent years, systematic mathematical and quantitative experimental analyses have made… read more here.
Keywords: ncrna mediated; modeling ncrna; cell fate; biology ... See more keywords
Mitochondrial Oxidative Phosphorylation Regulates the Fate Decision between Pathogenic Th17 and Regulatory T Cells.
Sign Up to like & getrecommendations! Published in 2020 at "Cell reports"
DOI: 10.1016/j.celrep.2020.01.022
Abstract: Understanding metabolic pathways that regulate Th17 development is important to broaden therapeutic options for Th17-mediated autoimmunity. Here, we report a pivotal role of mitochondrial oxidative phosphorylation (OXPHOS) for lineage specification toward pathogenic Th17 differentiation. Th17… read more here.
Keywords: fate decision; mitochondrial oxidative; th17; oxidative phosphorylation ... See more keywords
Seed fate and decision‐making processes in scatter‐hoarding rodents
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DOI: 10.1111/brv.12240
Abstract: A mechanistic understanding of seed movement and survival is important both for the development of theoretical models of plant population dynamics, spatial spread, and community assembly, and for the conservation and management of plant communities… read more here.
Keywords: seed; scatter hoarding; seed dispersal; seed fate ... See more keywords
Endothelial versus pronephron fate decision is modulated by the transcription factors Cloche/Npas4l, Tal1, and Lmo2
Sign Up to like & getrecommendations! Published in 2022 at "Science Advances"
DOI: 10.1126/sciadv.abn2082
Abstract: Endothelial specification is a key event during embryogenesis; however, when, and how, endothelial cells separate from other lineages is poorly understood. In zebrafish, Npas4l is indispensable for endothelial specification by inducing the expression of the… read more here.
Keywords: fate decision; transcription; npas4l tal1; pronephron ... See more keywords