Cell fate determination and Hippo signaling pathway in preimplantation mouse embryo.
Sign Up to like & getrecommendations! Published in 2021 at "Cell and tissue research"
DOI: 10.1007/s00441-021-03530-8
Abstract: First cell fate determination plays crucial roles in cell specification during early phases of embryonic development. Three classical concepts have been proposed to explain the lineage specification mechanism of the preimplantation embryo: inside-outside, pre-patterning, and… read more here.
Keywords: fate determination; preimplantation; cell fate; cell ... See more keywords
Flexible fate determination ensures robust differentiation in the hair follicle
Sign Up to like & getrecommendations! Published in 2018 at "Nature cell biology"
DOI: 10.1038/s41556-018-0232-y
Abstract: Tissue homeostasis is sustained by stem cell self-renewal and differentiation. How stem cells coordinately differentiate into multiple cell types is largely unclear. Recent studies underline the heterogeneity among stem cells or common progenitors, suggesting that… read more here.
Keywords: stem cells; hair; fate determination; differentiation ... See more keywords
Out or decay: fate determination of nuclear RNAs.
Sign Up to like & getrecommendations! Published in 2020 at "Essays in biochemistry"
DOI: 10.1042/ebc20200005
Abstract: In eukaryotes, RNAs newly synthesized by RNA polymerase II (RNAPII) undergo several processing steps prior to transport to the cytoplasm. It has long been known that RNAs with defects in processing or export are removed… read more here.
Keywords: rnas; fate; fate determination; nuclear rna ... See more keywords
Cation transporters in cell fate determination and plant adaptive responses to the low oxygen environment.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of experimental botany"
DOI: 10.1093/jxb/erab480
Abstract: Soil flooding creates low-oxygen environments in root zones and thus severely affects plant growth and productivity. Plants adapt to low-oxygen environments by a suit of orchestrated metabolic and anatomical alterations. Of these, formation of aerenchyma… read more here.
Keywords: oxygen; plant; fate determination; oxygen environment ... See more keywords
LncRNA-Smad7 mediates cross-talk between Nodal/TGF-β and BMP signaling to regulate cell fate determination of pluripotent and multipotent cells
Sign Up to like & getrecommendations! Published in 2022 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkac780
Abstract: Abstract Transforming growth factor β (TGF-β) superfamily proteins are potent regulators of cellular development and differentiation. Nodal/Activin/TGF-β and BMP ligands are both present in the intra- and extracellular milieu during early development, and cross-talk between… read more here.
Keywords: cell fate; bmp signaling; smad7; fate determination ... See more keywords
CHD1 regulates cell fate determination by activation of differentiation-induced genes
Sign Up to like & getrecommendations! Published in 2017 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkx377
Abstract: Abstract The coordinated temporal and spatial activation of gene expression is essential for proper stem cell differentiation. The Chromodomain Helicase DNA-binding protein 1 (CHD1) is a chromatin remodeler closely associated with transcription and nucleosome turnover… read more here.
Keywords: chd1; fate determination; differentiation; cell fate ... See more keywords
Endothelial Cell Fate Determination: A Top Notch Job in Vascular Decision-Making.
Sign Up to like & getrecommendations! Published in 2022 at "Cold Spring Harbor perspectives in medicine"
DOI: 10.1101/cshperspect.a041183
Abstract: As vascular networks form, endothelial cells (ECs) undergo cell fate decisions that determine whether they become tip or stalk cells of the developing vascular plexus or mature into arterial, venous, or lymphatic endothelium. EC fate… read more here.
Keywords: fate determination; cell fate; notch; fate ... See more keywords
3D genome perspective on cell fate determination, organ regeneration, and diseases
Sign Up to like & getrecommendations! Published in 2023 at "Cell Proliferation"
DOI: 10.1111/cpr.13482
Abstract: The nucleosome is the fundamental subunit of chromatin. Nucleosome structures are formed by the combination of histone octamers and genomic DNA. Through a systematic and precise process of folding and compression, these structures form a… read more here.
Keywords: cell fate; cell; fate determination; organ regeneration ... See more keywords
Reconstructing the regulatory circuit of cell fate determination in yeast mating response
Sign Up to like & getrecommendations! Published in 2017 at "PLoS Computational Biology"
DOI: 10.1371/journal.pcbi.1005671
Abstract: Massive technological advances enabled high-throughput measurements of proteomic changes in biological processes. However, retrieving biological insights from large-scale protein dynamics data remains a challenging task. Here we used the mating differentiation in yeast Saccharomyces cerevisiae… read more here.
Keywords: gene; cell; cell fate; fate determination ... See more keywords
Hyperthermia influences fate determination of neural stem cells with lncRNAs alterations in the early differentiation
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0171359
Abstract: Background Temperature is an important parameter in the microenvironment of neural stem cells (NSCs); however, little is known about the precise effects of hyperthermia on fate determination in NSCs or the role of long non-coding… read more here.
Keywords: stem cells; differentiation; neural stem; fate determination ... See more keywords
Sox11b regulates the migration and fate determination of Müller glia-derived progenitors during retina regeneration in zebrafish
Sign Up to like & getrecommendations! Published in 2022 at "Neural Regeneration Research"
DOI: 10.4103/1673-5374.346550
Abstract: The transcription factor Sox11 plays important roles in retinal neurogenesis during vertebrate eye development. However, its function in retina regeneration remains elusive. Here we report that Sox11b, a zebrafish Sox11 homolog, regulates the migration and… read more here.
Keywords: regeneration; migration fate; fate determination; migration ... See more keywords