Articles with "fate mapping" as a keyword



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Fate Mapping via Ms4a3-Expression History Traces Monocyte-Derived Cells

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Published in 2019 at "Cell"

DOI: 10.1016/j.cell.2019.08.009

Abstract: Most tissue-resident macrophage (RTM) populations are seeded by waves of embryonic hematopoiesis and are self-maintained independently of a bone marrow contribution during adulthood. A proportion of RTMs, however, is constantly replaced by blood monocytes, and… read more here.

Keywords: via ms4a3; fate mapping; mapping via; derived cells ... See more keywords
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Fate-Mapping of GM-CSF Expression Identifies a Discrete Subset of Inflammation-Driving T Helper Cells Regulated by Cytokines IL-23 and IL-1β.

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Published in 2019 at "Immunity"

DOI: 10.1016/j.immuni.2019.04.006

Abstract: Pathogenic lymphocytes initiate the development of chronic inflammatory diseases. The cytokine granulocyte-macrophage colony-stimulating factor (GM-CSF) (encoded by Csf2) is a key communicator between pathogenic lymphocytes and tissue-invading inflammatory phagocytes. However, the molecular properties of GM-CSF-producing cells… read more here.

Keywords: fate mapping; csf expression; mapping csf; csf ... See more keywords
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Fate mapping of single NK cells identifies a type 1 innate lymphoid-like lineage that bridges innate and adaptive recognition of viral infection

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Published in 2021 at "Immunity"

DOI: 10.1016/j.immuni.2021.08.002

Abstract: Summary Upon viral infection, natural killer (NK) cells expressing certain germline-encoded receptors are selected, expanded, and maintained in an adaptive-like manner. Currently, these are thought to differentiate along a common pathway. However, by fate mapping… read more here.

Keywords: fate mapping; mapping single; type innate; infection ... See more keywords
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Genetic fate-mapping reveals surface accumulation but not deep organ invasion of pleural and peritoneal cavity macrophages following injury

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Published in 2021 at "Nature Communications"

DOI: 10.1038/s41467-021-23197-7

Abstract: During injury, monocytes are recruited from the circulation to inflamed tissues and differentiate locally into mature macrophages, with prior reports showing that cavity macrophages of the peritoneum and pericardium invade deeply into the respective organs… read more here.

Keywords: fate mapping; mapping reveals; cavity macrophages; cavity ... See more keywords
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Fate mapping of neural stem cell niches reveals distinct origins of human cortical astrocytes

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Published in 2022 at "Science"

DOI: 10.1126/science.abm5224

Abstract: Progenitors of the developing human neocortex reside in the ventricular and outer subventricular zones (VZ and OSVZ, respectively). However, whether cells derived from these niches have similar developmental fates is unknown. By performing fate mapping… read more here.

Keywords: cell; white matter; brain; fate mapping ... See more keywords
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Genetic Fate Mapping Defines the Vascular Potential of Endocardial Cells in the Adult Heart

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Published in 2018 at "Circulation Research"

DOI: 10.1161/circresaha.117.312354

Abstract: Rationale: Endocardium is the major source of coronary endothelial cells (ECs) in the fetal and neonatal hearts. It remains unclear whether endocardium in the adult stage is also the main origin of neovascularization after cardiac… read more here.

Keywords: adult endocardial; fate mapping; endocardial cells; vascular potential ... See more keywords
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Identification of novel B-1 transitional progenitors by B-1 lymphocyte fate-mapping transgenic mouse model Bhlhe41 dTomato-Cre

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Published in 2022 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2022.946202

Abstract: B-1 lymphocytes exhibit specialized roles in host defense against multiple pathogens. Despite the fact that CD19+CD93+B220lo/- B cells have been identified as B-1 progenitors, the definition for B-1 progenitors remains to be elucidated as CD19+CD93+B220+… read more here.

Keywords: bhlhe41 dtomato; cre; dtomato cre; fate mapping ... See more keywords