Dissecting the dynamics of signaling events in the BMP, WNT, and NODAL cascade during self-organized fate patterning in human gastruloids
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DOI: 10.1371/journal.pbio.3000498
Abstract: During gastrulation, the pluripotent epiblast self-organizes into the 3 germ layers—endoderm, mesoderm and ectoderm, which eventually form the entire embryo. Decades of research in the mouse embryo have revealed that a signaling cascade involving the… read more here.
Keywords: cascade; wnt nodal; bmp wnt; gastrulation ... See more keywords