NLRP3 inflammasome activation mediates fatigue-like behaviors in mice via neuroinflammation
Sign Up to like & getrecommendations! Published in 2017 at "Neuroscience"
DOI: 10.1016/j.neuroscience.2017.06.048
Abstract: Numerous experimental and clinical studies have suggested that the interaction between the immune system and the brain plays an important role in the pathophysiology of chronic fatigue syndrome (CFS). The NLRP3 inflammasome is an important… read more here.
Keywords: inflammasome activation; like behaviors; fatigue like; mice ... See more keywords
Induction of fatigue-like behavior by pelvic irradiation of male mice alters cognitive behaviors and BDNF expression
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DOI: 10.1371/journal.pone.0235566
Abstract: Fatigue and cognitive deficits are often co-occurring symptoms reported by patients after radiation therapy for prostate cancer. In this study, we induced fatigue-like behavior in mice using targeted pelvic irradiation to mimic the clinical treatment… read more here.
Keywords: induction fatigue; fatigue; like behavior; fatigue like ... See more keywords