Association of Use of Omega-3 Polyunsaturated Fatty Acids With Changes in Severity of Anxiety Symptoms
Sign Up to like & getrecommendations! Published in 2018 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2018.2327
Abstract: Key Points Question Is omega-3 polyunsaturated fatty acid treatment associated with an improvement in anxiety symptoms? Findings In this systematic review and meta-analysis of 19 clinical trials including 2240 participants from 11 countries, improvement in… read more here.
Keywords: anxiety symptoms; polyunsaturated fatty; omega polyunsaturated; fatty acid ... See more keywords
There Is No Magic Pill to Prevent Frailty-You Still Have to Eat Your Vegetables.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA network open"
DOI: 10.1001/jamanetworkopen.2022.31147
Abstract: Frailty among older adults is not a normal part of aging, but is common and can lead to an increased incidence of fractures, hospitalizations, and deaths, among other problems. 1 The Mediterranean diet has been… read more here.
Keywords: frailty index; fatty acid; frailty; omega fatty ... See more keywords
Effect of Vitamin D3 and Omega-3 Fatty Acid Supplementation on Risk of Frailty
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.31206
Abstract: Key Points Question Does supplementation with vitamin D3 and/or omega-3 fatty acids reduce the risk of frailty? Findings In this ancillary study of a randomized clinical trial including 25 871 individuals aged 50 years or older,… read more here.
Keywords: supplementation; vitamin omega; fatty acid; frailty ... See more keywords
A key role of nuclear factor Y in the refeeding response of fatty acid synthase in adipocytes
Sign Up to like & getrecommendations! Published in 2017 at "FEBS Letters"
DOI: 10.1002/1873-3468.12620
Abstract: Fatty acid synthase (Fasn) is a key component of energy metabolism that is dynamically induced by food intake. Although extensive studies have revealed a number of transcription factors involved in the fasting/refeeding transition of Fasn… read more here.
Keywords: acid synthase; fatty acid; nuclear factor; refeeding response ... See more keywords
Investigation of the putative rate‐limiting role of electron transfer in fatty acid desaturation using transfected HEK293T cells
Sign Up to like & getrecommendations! Published in 2019 at "FEBS Letters"
DOI: 10.1002/1873-3468.13622
Abstract: Elevated fatty acid (FA) levels contribute to severe metabolic diseases. Unbalanced oversupply of saturated FAs is particularly damaging, which renders stearoyl‐CoA desaturase (SCD1) activity an important factor of resistance. A SCD1‐related oxidoreductase protects cells against… read more here.
Keywords: hek293t cells; fatty acid; electron transfer; rate limiting ... See more keywords
Identification of the fatty acid coenzyme‐A ligase FadD1 as an interacting partner of FptX in the Pseudomonas aeruginosa pyochelin pathway
Sign Up to like & getrecommendations! Published in 2020 at "FEBS Letters"
DOI: 10.1002/1873-3468.14012
Abstract: Pseudomonas aeruginosa is one of the most important nosocomial bacteria emerging as a highly multidrug‐resistant pathogen. P. aeruginosa produces two siderophores including pyochelin (PCH) to fulfil its need for iron during infections. We know that… read more here.
Keywords: pseudomonas aeruginosa; ligase fadd1; fatty acid; acid coenzyme ... See more keywords
Thermodynamic and biophysical study of fatty acid effector binding to soybean lipoxygenase: implications for allostery driven by helix α2 dynamics
Sign Up to like & getrecommendations! Published in 2022 at "FEBS Letters"
DOI: 10.1002/1873-3468.14275
Abstract: Previous comparative kinetic isotope effects have inferred an allosteric site for fatty acids and their derivatives that modulates substrate selectivity in 15‐lipoxygenases. Hydrogen–deuterium exchange also previously revealed regionally defined enhanced protein flexibility, centred at helix… read more here.
Keywords: thermodynamic biophysical; biophysical study; fatty acid; soybean lipoxygenase ... See more keywords
HRD1 inhibits fatty acid oxidation and tumorigenesis by ubiquitinating CPT2 in triple‐negative breast cancer
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Oncology"
DOI: 10.1002/1878-0261.12856
Abstract: Dependence on glutamine and acceleration of fatty acid oxidation (FAO) are both metabolic characteristics of triple‐negative breast cancer (TNBC). With the rapid growth of tumors, accelerated glutamine catabolism depletes local glutamine, resulting in glutamine deficiency.… read more here.
Keywords: negative breast; hrd1; fatty acid; breast cancer ... See more keywords
Enhancing cancer‐associated fibroblast fatty acid catabolism within a metabolically challenging tumor microenvironment drives colon cancer peritoneal metastasis
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Oncology"
DOI: 10.1002/1878-0261.12917
Abstract: Most cancer‐related deaths result from the progressive growth of metastases. Patients with peritoneal metastatic (PM) colorectal cancer have reduced overall survival. Currently, it is still unclear why colorectal cancer (CRC) cells home to and proliferate… read more here.
Keywords: fatty acid; colorectal cancer; colon cancer; cancer ... See more keywords
Bioinspired Fatty Acid Amide‐Based Slippery Oleogels for Shear‐Stable Lubrication
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DOI: 10.1002/advs.202105528
Abstract: Liquid‐repellent technology is an efficient means of energy‐saving and biofouling avoidance. However, liquid‐repellent surfaces suffer from inefficient lubricant retention under shear flow and fouling problem in marine environment. Here, the authors demonstrate a fatty acid… read more here.
Keywords: lubrication; marine; stable lubrication; acid amide ... See more keywords
Upregulation of Superenhancer‐Driven LncRNA FASRL by USF1 Promotes De Novo Fatty Acid Biosynthesis to Exacerbate Hepatocellular Carcinoma (Adv. Sci. 1/2023)
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202204711
Abstract: Superenhancers drive abnormal gene expression in tumors and promote malignancy. However, the relationship between superenhancer‐associated long noncoding RNA (lncRNA) and abnormal metabolism is unknown. This study identifies a novel lncRNA, fatty acid synthesis‐related lncRNA (FASRL),… read more here.
Keywords: hepatocellular carcinoma; acid synthesis; fasrl; lncrna fasrl ... See more keywords