Articles with "fatty acyl" as a keyword



A method for the quantitative determination of glycerophospholipid regioisomers by UPLC-ESI-MS/MS

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Published in 2018 at "Analytical and Bioanalytical Chemistry"

DOI: 10.1007/s00216-018-1517-5

Abstract: Diacyl glycerophospholipids (GPs) belong to the most abundant lipid species in living organisms and consist of a glycerol backbone with fatty acyl groups in sn-1 and sn-2 and a polar head group in the sn-3… read more here.

Keywords: diacyl; mixed diacyl; method quantitative; method ... See more keywords

Identification of adaptive inhibitors of Cryptosporidium parvum fatty acyl-coenzyme A synthetase isoforms by virtual screening

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Published in 2019 at "Parasitology Research"

DOI: 10.1007/s00436-019-06445-0

Abstract: Cryptosporidiosis is a significant cause of gastroenteritis in both humans and livestock in developing countries. The only FDA-approved drug available against the same is nitazoxanide, with questionable efficacy in malnourished children and immunocompromised patients. Recent… read more here.

Keywords: virtual screening; cryptosporidium parvum; acyl coenzyme; coenzyme synthetase ... See more keywords
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A New N-Fatty Acyl Tryptamine from Annana atemoya

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Published in 2020 at "Chemistry of Natural Compounds"

DOI: 10.1007/s10600-020-03235-4

Abstract: A new N-fatty acyl tryptamine, N-nonadecanoyl-4,5-dihydroxytryptamine (1), was isolated from the stems of Annona atemoya. The structure of the new tryptamine-derived amide was elucidated by chemical and physical evidence. read more here.

Keywords: fatty acyl; annana atemoya; acyl tryptamine; new fatty ... See more keywords

Metal Oxide Laser Ionization Mass Spectrometry Imaging (MOLI MSI) Using Cerium(IV) Oxide.

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Published in 2019 at "Analytical chemistry"

DOI: 10.1021/acs.analchem.9b00894

Abstract: Matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI MSI) is a powerful technique for spatially resolved metabolomics. A variation on MALDI, termed metal oxide laser ionization (MOLI), capitalizes on the unique property of cerium(IV) oxide (CeO2)… read more here.

Keywords: mass spectrometry; msi; ionization mass; moli msi ... See more keywords

Insight into the Feasibility of Fatty Acyl Chlorides with 10-18 Carbons for the Ball-Milling Synthesis of Thermoplastic Cellulose Esters.

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Published in 2024 at "Biomacromolecules"

DOI: 10.1021/acs.biomac.3c01354

Abstract: Fatty acid cellulose esters (FACE) are common cellulose-based thermoplastics, and their thermoplasticity is determined by both the contents and the lengths of the side chains. Herein, various FACE were synthesized by the ball-milling esterification of… read more here.

Keywords: acyl chlorides; ball milling; cellulose esters; fatty acyl ... See more keywords

Functional Characterization of a Fatty Acyl Reductase Identified from the Female Pheromone Gland of Mythimna loreyi (Lepidoptera: Noctuidae).

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Published in 2025 at "Journal of agricultural and food chemistry"

DOI: 10.1021/acs.jafc.5c08131

Abstract: Sex pheromones, which play a critical role in mediating sexual communication of Lepidoptera, are biosynthesized by a variety of particular enzymes in specialized pheromone glands (PGs). Among these enzymes, fatty acyl-CoA reductases (FARs) catalyze the… read more here.

Keywords: pheromone; lepidoptera; fatty acyl; functional characterization ... See more keywords
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Effect of Hydrophobicity on the Anticancer Activity of Fatty-Acyl-Conjugated CM4 in Breast Cancer Cells

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Published in 2020 at "ACS Omega"

DOI: 10.1021/acsomega.0c02093

Abstract: Antimicrobial peptides (AMPs) are important anticancer resources, and exploring AMP conjugates as highly effective and selective anticancer agents would represent new progress in cancer treatment. In this study, we synthesized C4–C16 fatty-acyl-conjugated AMP CM4 and… read more here.

Keywords: acyl; breast cancer; cm4; fatty acyl ... See more keywords

Functional diversification of teleost Fads2 fatty acyl desaturases occurs independently of the trophic level

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Published in 2019 at "Scientific Reports"

DOI: 10.1038/s41598-019-47709-0

Abstract: The long-chain (≥C20) polyunsaturated fatty acid biosynthesis capacity of fish varies among species, with trophic level hypothesised as a major factor. The biosynthesis capacity is largely dependent upon the presence of functionally diversified fatty acyl… read more here.

Keywords: trophic level; diversification teleost; teleost fads2; fads2 ... See more keywords

Bivalent recognition of fatty acyl-CoA by a human integral membrane palmitoyltransferase

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Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"

DOI: 10.1073/pnas.2022050119

Abstract: Significance Protein palmitoylation is one of the most highly abundant protein modifications, through which long-chain fatty acids get attached to cysteines by a thioester linkage. It plays critically important roles in growth signaling, the organization… read more here.

Keywords: integral membrane; chemistry; palmitoyl coa; coa ... See more keywords

Ribosomally derived lipopeptides containing distinct fatty acyl moieties

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Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"

DOI: 10.1073/pnas.2113120119

Abstract: Significance Fatty-acylated lipopeptides are metabolites of high medical and biotechnological importance, exemplified by the clinically used daptomycin, polymyxin, and echinocandin anti-infectives. The known representatives are produced by giant nonribosomal enzymes that usually generate heterogeneously acylated… read more here.

Keywords: fatty acylated; distinct fatty; acyl moieties; fatty acyl ... See more keywords

Fatty acyl recognition and transfer by an integral membrane S-acyltransferase

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Published in 2018 at "Science"

DOI: 10.1126/science.aao6326

Abstract: Fattening up proteins Many eukaryotic proteins are modified by the attachment of lipids, and these modifications can alter how proteins interact with cellular membranes. Rana et al. present x-ray crystal structures of an integral membrane… read more here.

Keywords: chain; fatty acyl; dhhc; membrane ... See more keywords