Novel Isotope-Labeled Derivatization Strategy for the Simultaneous Analysis of Fatty Acids and Fatty Alcohols and Its Application in Idiopathic Inflammatory Myopathies and Pancreatic Cancer.
Sign Up to like & getrecommendations! Published in 2023 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c05558
Abstract: Fatty acids (FAs) and fatty alcohols (FOHs) are essential compounds for maintaining life. Due to the inherent poor ionization efficiency, low abundance, and complex matrix effect, such metabolites are challenging to precisely quantify and explore… read more here.
Keywords: fas fohs; fatty alcohols; novel isotope; fatty acids ... See more keywords
Engineering Saccharomyces cerevisiae for Efficient Biosynthesis of Fatty Alcohols Based on Enhanced Supply of Free Fatty Acids
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DOI: 10.1021/acsomega.7b00065
Abstract: In recent years, production of fatty acid derivatives has attracted much attention because of their wide range of applications in renewable oleochemicals. Microorganisms such as Saccharomyces cerevisiae provided an ideal cell factory for such chemical… read more here.
Keywords: supply; saccharomyces cerevisiae; alcohols based; based enhanced ... See more keywords
Photobiocatalytic synthesis of chiral secondary fatty alcohols from renewable unsaturated fatty acids
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-16099-7
Abstract: En route to a bio-based chemical industry, the conversion of fatty acids into building blocks is of particular interest. Enzymatic routes, occurring under mild conditions and excelling by intrinsic selectivity, are particularly attractive. Here we… read more here.
Keywords: fatty acids; fatty alcohols; secondary fatty; enantiomerically pure ... See more keywords
Renewable linear alpha-olefins by base-catalyzed dehydration of biologically-derived fatty alcohols
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DOI: 10.1039/d1gc00243k
Abstract: McClelland, D.J., et al. 2021. “Renewable Linear Alpha-Olefins by Base-Catalyzed Dehydration of Biologically-Derived Fatty Alcohols.” Green Chemistry. DOI: 10.1039/D1GC00243K. Background/objective Linear alpha olefins (LAOs) are widely used to produce plasticizers, surfactants, lubricants, and polyethylene comonomers.… read more here.
Keywords: renewable linear; linear alpha; chemistry; alpha olefins ... See more keywords
Non-homologous End Joining-Mediated Insertional Mutagenesis Reveals a Novel Target for Enhancing Fatty Alcohols Production in Yarrowia lipolytica
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.898884
Abstract: Non-homologous end joining (NHEJ)-mediated integration is effective in generating random mutagenesis to identify beneficial gene targets in the whole genome, which can significantly promote the performance of the strains. Here, a novel target leading to… read more here.
Keywords: homologous end; fatty alcohols; non homologous; novel target ... See more keywords