CRISPR/Cas9 in zebrafish: An attractive model for FBN1 genetic defects in humans.
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DOI: 10.1002/mgg3.1775
Abstract: BACKGROUND Mutations in the fibrillin-1 gene (FBN1) are associated with various heritable connective tissue disorders (HCTD). The most studied HCTD is Marfan syndrome. Ninety percent of Marfan syndrome is caused by mutations in the FBN1… read more here.
Keywords: fbn1; crispr cas9; fbn1 zebrafish; model ... See more keywords