Articles with "fbw7 phase" as a keyword



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The stability of Fbw7α in M-phase requires its phosphorylation by PKC

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Published in 2017 at "PLoS ONE"

DOI: 10.1371/journal.pone.0183500

Abstract: Fbw7 is a tumor suppressor often deleted or mutated in human cancers. It serves as the substrate-recruiting subunit of a SCF ubiquitin ligase that targets numerous critical proteins for degradation, including oncoproteins and master transcription… read more here.

Keywords: stability fbw7; phase requires; fbw7; fbw7 phase ... See more keywords