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1
Published in 2020 at "Blood Cancer Journal"
DOI: 10.1038/s41408-020-00362-7
Abstract: Myelodysplastic syndrome (MDS) is a heterogeneous myeloid malignancy characterized by blood cell morphological dysplasia, ineffective clonal hematopoiesis, and risk of transformation to secondary acute myeloid leukemia (sAML). A number of genetic abnormalities have been identified…
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Keywords:
tumor suppressor;
myelodysplastic syndrome;
fbxo11;
transformation ... See more keywords
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3
Published in 2023 at "Life Science Alliance"
DOI: 10.26508/lsa.202201735
Abstract: FBXO11 regulates the expression of the complement receptor C5aR1 and the inflammatory cytokine IL-1β, affecting how macrophages respond to Staphylococcus aureus pore–forming toxins. Staphylococcus aureus causes severe infections such as pneumonia and sepsis depending on…
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Keywords:
c5ar1;
inflammation;
fbxo11;
expression ... See more keywords