Activation of the integrated stress response is a vulnerability for multidrug‐resistant FBXW7‐deficient cells
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DOI: 10.15252/emmm.202215855
Abstract: FBXW7 is one of the most frequently mutated tumor suppressors, deficiency of which has been associated with resistance to some anticancer therapies. Through bioinformatics and genome‐wide CRISPR screens, we here reveal that FBXW7 deficiency leads… read more here.
Keywords: deficient cells; stress response; integrated stress; fbxw7 deficient ... See more keywords