FBXW7β isoform drives transcriptional activation of the proinflammatory TNF cluster in human pro-B cells
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DOI: 10.1182/bloodadvances.2022007910
Abstract: Key Points • Previously thought to be restricted to neural tissues, FBXW7β is the predominant FBXW7 isoform in normal and malignant human pro-B cells.• FBXW7β promotes transcriptional activation of the proinflammatory gene cluster that contains… read more here.
Keywords: transcriptional activation; pro cells; human pro; activation proinflammatory ... See more keywords