FBXW7 missense mutation: a novel negative prognostic factor in metastatic colorectal adenocarcinoma
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DOI: 10.18632/oncotarget.16848
Abstract: Background FBXW7 functions as a ubiquitin ligase tagging multiple dominant oncogenic proteins and commonly mutates in colorectal cancer. Data suggest missense mutations lead to greater loss of FBXW7 function than other gene aberrations do. However,… read more here.
Keywords: metastatic colorectal; fbxw7 missense; missense mutations; negative prognostic ... See more keywords