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Tackling quantitative polymorphic analysis through fixed-dose combination tablets production. Pyrazinamide polymorphic assessment.

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Published in 2020 at "Journal of pharmaceutical and biomedical analysis"

DOI: 10.1016/j.jpba.2020.113786

Abstract: Pyrazinamide (PZA), Rifampicin (RIF), Isoniazid (ISH) and Ethambutol (ETB) form the core for the treatment of Tuberculosis, today a devastating disease in low-income populations around the world. These drugs are usually administrated by fixed-dose combination… read more here.

Keywords: fdc tablets; drug substance; dose combination; form ... See more keywords