Low Endogenous Fibroblast Growth Factor 2 Levels Are Associated With Heightened Conditioned Fear Expression in Rats and Humans
Sign Up to like & getrecommendations! Published in 2017 at "Biological Psychiatry"
DOI: 10.1016/j.biopsych.2017.03.020
Abstract: BACKGROUND Hippocampal concentrations of the neurotrophic factor fibroblast growth factor 2 (FGF2) are negatively associated with the expression of fear following conditioning in rats. Heightened conditioned fear expression may be a prospective risk factor for… read more here.
Keywords: expression rats; fear expression; conditioned fear; expression ... See more keywords
Stress-Induced Differential Regulation Leads to Decoupling of the Activity between mPFC and Amygdala
Sign Up to like & getrecommendations! Published in 2017 at "Biophysical Journal"
DOI: 10.1016/j.bpj.2016.11.748
Abstract: Exposure to severe stress leads to the development of psychiatric disorders. Clinical studies have shown that three brain areas involved in learning and memory—the hippocampus, amygdala and medial prefrontal cortex (mPFC)—undergo distinct changes with stress… read more here.
Keywords: mpfc; fear expression; stress; amygdala ... See more keywords
Fear expression is suppressed by tyrosine administration
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-52610-x
Abstract: Animal studies have demonstrated that catecholamines regulate several aspects of fear conditioning. In humans, however, pharmacological manipulations of the catecholaminergic system have been scarce, and their primary focus has been to interfering with catecholaminergic activity… read more here.
Keywords: suppressed tyrosine; expression suppressed; fear expression; tyrosine administration ... See more keywords
Alteration of fear behaviors in sleep-deprived adolescent rats: increased fear expression and delayed fear extinction
Sign Up to like & getrecommendations! Published in 2021 at "Animal Cells and Systems"
DOI: 10.1080/19768354.2021.1902854
Abstract: ABSTRACT Disruption of sleep due to acute or chronic stress can lead to changes in emotional memory processing. Sleep disturbances are highly prevalent in post-traumatic stress disorder (PTSD), but still, the contribution of sleep deprivation… read more here.
Keywords: fear; fear extinction; adolescent rats; fear expression ... See more keywords