Left Habenular Activity Attenuates Fear Responses in Larval Zebrafish
Sign Up to like & getrecommendations! Published in 2017 at "Current Biology"
DOI: 10.1016/j.cub.2017.06.017
Abstract: Fear responses are defensive states that ensure survival of an organism in the presence of a threat. Perception of an aversive cue causes changes in behavior and physiology, such as freezing and elevated cortisol, followed by… read more here.
Keywords: fear responses; dhb ipn; left dhb; left habenular ... See more keywords
Towards an unconscious neural reinforcement intervention for common fears
Sign Up to like & getrecommendations! Published in 2018 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.1721572115
Abstract: Significance Conventional therapies for the treatment of anxiety disorders are aversive, and as a result, many patients terminate treatment prematurely. We have developed an unconscious method to bypass the unpleasantness in conscious exposure using functional… read more here.
Keywords: intervention; fear responses; reinforcement; physiological fear ... See more keywords
Transition ability to safe states reduces fear responses to height
Sign Up to like & getrecommendations! Published in 2025 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2416920122
Abstract: Significance Previous studies on fear extinction have relied on repeated exposure to fear-inducing contexts without negative consequences, which gradually constructs a new association between the contexts and nonaversive outcomes. However, fear extinction may also be… read more here.
Keywords: fear extinction; responses height; fear responses; transition ability ... See more keywords
A Brain-Inspired Visual Fear Responses Model for UAV Emergent Obstacle Dodging
Sign Up to like & getrecommendations! Published in 2020 at "IEEE Transactions on Cognitive and Developmental Systems"
DOI: 10.1109/tcds.2019.2939024
Abstract: Dodging emergent dangers is an innate cognitive ability for animals, which helps them to survive in the natural environment. The retina-superior colliculus (SC)-pulvinar–amygdala–periaqueductal gray pathway is responsible for the visual fear responses, and it is… read more here.
Keywords: fear; visual fear; model; fear responses ... See more keywords
Extinction and subsequent updating of innate fear responses to a visual looming stimulus rely on hippocampus-dependent mechanisms
Sign Up to like & getrecommendations! Published in 2025 at "PLOS Biology"
DOI: 10.1371/journal.pbio.3003391
Abstract: Animals rely on innate and learned behaviour to respond to their environment, but how the brain balances hardwired responses with adaptive flexibility remains unclear. Here, we demonstrate that innate looming stimulus responses in mice can… read more here.
Keywords: responses visual; looming stimulus; visual looming; fear responses ... See more keywords
Cortisol Imbalance and Fear Learning in PTSD: Therapeutic Approaches to Control Abnormal Fear Responses
Sign Up to like & getrecommendations! Published in 2025 at "Current Neuropharmacology"
DOI: 10.2174/1570159x23666250123142526
Abstract: Post-Traumatic Stress Disorder (PTSD) is mainly characterized by dysregulated fear responses, including hyperarousal and intrusive re-experiencing of traumatic memories. This work delves into the intricate interplay between abnormal fear responses, cortisol dysregulation, and the Hypothalamic-Pituitary-Adrenal… read more here.
Keywords: abnormal fear; fear; ptsd; fear responses ... See more keywords
Oxytocin Promotes Accurate Fear Discrimination and Adaptive Defensive Behaviors
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2020.583878
Abstract: The nonapeptide, oxytocin (OT), known for its role in social bonding and attachment formation, has demonstrated anxiolytic properties in animal models and human studies. However, its role in the regulation of fear responses appears more… read more here.
Keywords: fear responses; fear discrimination; fear; salience ... See more keywords