In Silico Identification of Key Genes and Immune Infiltration Characteristics in Epicardial Adipose Tissue from Patients with Coronary Artery Disease
Sign Up to like & getrecommendations! Published in 2022 at "BioMed Research International"
DOI: 10.1155/2022/5610317
Abstract: Background The present study is aimed at identifying the differentially expressed genes (DEGs) and relevant biological processes and pathways associated with epicardial adipose tissue (EAT) from patients with coronary artery disease (CAD). We also explored… read more here.
Keywords: infiltration; feature; epicardial adipose; feature genes ... See more keywords
FOXO4 May Be a Biomarker of Postmenopausal Osteoporosis
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of General Medicine"
DOI: 10.2147/ijgm.s347416
Abstract: Purpose Postmenopausal osteoporosis (PMOP) is a common and debilitating chronic disease, but it has just no cure options. The objective of this study was to identify genes associated with osteoporosis and reveal potential therapeutic targets.… read more here.
Keywords: feature genes; differentially expressed; postmenopausal osteoporosis; foxo4 may ... See more keywords
Novel Immune-Related Genetic Expression for Primary Sjögren's Syndrome
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2021.719958
Abstract: Objective: To identify novel immune-related genes expressed in primary Sjögren's syndrome (pSS). Methods: Gene expression profiles were obtained from the Gene Expression Omnibus (GEO) database, and differentially expressed genes (DEGs) were screened. The differences in… read more here.
Keywords: expression; feature genes; gren syndrome; immune related ... See more keywords
Immunogenic cell death-led discovery of COVID-19 biomarkers and inflammatory infiltrates
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2023.1191004
Abstract: Immunogenic cell death (ICD) serves a critical role in regulating cell death adequate to activate an adaptive immune response, and it is associated with various inflammation-related diseases. However, the specific role of ICD-related genes in… read more here.
Keywords: cell death; covid; immunogenic cell; feature genes ... See more keywords
Exploration of novel biomarkers in Alzheimer’s disease based on four diagnostic models
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Aging Neuroscience"
DOI: 10.3389/fnagi.2023.1079433
Abstract: Background Despite tremendous progress in diagnosis and prediction of Alzheimer’s disease (AD), the absence of treatments implies the need for further research. In this study, we screened AD biomarkers by comparing expression profiles of AD… read more here.
Keywords: alzheimer disease; optimal diagnostic; feature genes; analysis ... See more keywords
Identification of feature genes and pathways for Alzheimer's disease via WGCNA and LASSO regression
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Computational Neuroscience"
DOI: 10.3389/fncom.2022.1001546
Abstract: While Alzheimer's disease (AD) can cause a severe economic burden, the specific pathogenesis involved is yet to be elucidated. To identify feature genes associated with AD, we downloaded data from three GEO databases: GSE122063, GSE15222,… read more here.
Keywords: lasso regression; alzheimer disease; feature; feature genes ... See more keywords
Screening of Gene Expression Markers for Corona Virus Disease 2019 Through Boruta_MCFS Feature Selection
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Public Health"
DOI: 10.3389/fpubh.2022.901602
Abstract: Since the first report of SARS-CoV-2 virus in Wuhan, China in December 2019, a global outbreak of Corona Virus Disease 2019 (COVID-19) pandemic has been aroused. In the prevention of this disease, accurate diagnosis of… read more here.
Keywords: disease; feature; feature genes; boruta mcfs ... See more keywords
XGBoost-Based Feature Learning Method for Mining COVID-19 Novel Diagnostic Markers
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Public Health"
DOI: 10.3389/fpubh.2022.926069
Abstract: In December 2019, an outbreak of novel coronavirus pneumonia spread over Wuhan, Hubei Province, China, which then developed into a significant global health public event, giving rise to substantial economic losses. We downloaded throat swab… read more here.
Keywords: novel diagnostic; feature; feature genes; method ... See more keywords
Construction of a 26-feature gene support vector machine classifier for smoking and non-smoking lung adenocarcinoma sample classification
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DOI: 10.3892/mmr.2017.8220
Abstract: The present study aimed to identify the feature genes associated with smoking in lung adenocarcinoma (LAC) samples and explore the underlying mechanism. Three gene expression datasets of LAC samples were downloaded from the Gene Expression… read more here.
Keywords: classifier; feature; construction; feature genes ... See more keywords
Feature genes in metastatic breast cancer identified by MetaDE and SVM classifier methods
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Medicine Reports"
DOI: 10.3892/mmr.2018.8398
Abstract: The aim of the present study was to investigate the feature genes in metastatic breast cancer samples. A total of 5 expression profiles of metastatic breast cancer samples were downloaded from the Gene Expression Omnibus… read more here.
Keywords: feature genes; breast cancer; svm classifier;