Sequence features of variable region determining physicochemical properties and polyreactivity of therapeutic antibodies.
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DOI: 10.1016/j.molimm.2019.06.012
Abstract: Therapeutic antibodies have transformed the clinical practice. Not surprisingly, development of antibody therapeutics is currently the main focus of the biotechnology industry. Nonetheless, the development process is complex, and many antibodies do not reach the… read more here.
Keywords: therapeutic antibodies; features variable; polyreactivity; variable region ... See more keywords