Anakinra usage in febrile infection related epilepsy syndrome: an international cohort
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DOI: 10.1002/acn3.51229
Abstract: Febrile‐infection related epilepsy syndrome (FIRES) is a devastating neurological condition characterized by a febrile illness preceding new onset refractory status epilepticus (NORSE). Increasing evidence suggests innate immune dysfunction as a potential pathological mechanism. We report… read more here.
Keywords: febrile infection; infection; related epilepsy; infection related ... See more keywords
Functional deficiency in endogenous interleukin‐1 receptor antagonist in patients with febrile infection‐related epilepsy syndrome
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DOI: 10.1002/ana.25439
Abstract: We recently reported successful treatment of a child with febrile infection‐related epilepsy syndrome (FIRES), a subtype of new onset refractory status epilepticus, with the recombinant interleukin‐1 (IL1) receptor antagonist (IL1RA) anakinra. On this basis, we… read more here.
Keywords: receptor antagonist; febrile infection; infection related; related epilepsy ... See more keywords
Proposal to optimize evaluation and treatment of Febrile infection‐related epilepsy syndrome (FIRES): A Report from FIRES workshop
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DOI: 10.1002/epi4.12447
Abstract: Febrile infection‐related epilepsy syndrome (FIRES) is a rare catastrophic epileptic encephalopathy that presents suddenly in otherwise normal children and young adults causing significant neurological disability, chronic epilepsy, and high rates of mortality. To suggest a… read more here.
Keywords: febrile infection; infection related; related epilepsy; syndrome fires ... See more keywords
Cannabidiol in the acute phase of febrile infection‐related epilepsy syndrome (FIRES)
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DOI: 10.1002/epi4.12740
Abstract: Febrile infection‐related epilepsy syndrome (FIRES) is a prolonged refractory status epilepticus (SE) that develops among healthy individuals after a febrile infection. FIRES treatment is challenging due to its poor response to antiseizure medications (ASMs) and… read more here.
Keywords: acute phase; febrile infection; infection related; phase ... See more keywords
Febrile infection-related epilepsy syndrome (FIRES) in an adult patient: an early neuroradiological finding
Sign Up to like & getrecommendations! Published in 2019 at "Neurological Sciences"
DOI: 10.1007/s10072-019-03925-0
Abstract: Dear Editor, New onset refractory status epilepticus (NORSE) is a clinical presentation in a patient without active epilepsy or other pre-existing relevant neurological disorders, with new onset of refractory status epilepticus without a clear acute… read more here.
Keywords: febrile infection; etiology; infection related; infection ... See more keywords
New-onset refractory status epilepticus and febrile infection-related epilepsy syndrome
Sign Up to like & getrecommendations! Published in 2023 at "Current Opinion in Neurology"
DOI: 10.1097/wco.0000000000001137
Abstract: Purpose of review The concept and understanding of new-onset refractory status epilepticus (NORSE), and its subtype with prior fever known as febrile infection-related epilepsy syndrome (FIRES) have evolved in the recent past. This review aims… read more here.
Keywords: refractory status; status epilepticus; febrile infection; onset refractory ... See more keywords
International consensus recommendations for management of new onset refractory status epilepticus including febrile infection‐related epilepsy syndrome: Statements and supporting evidence
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DOI: 10.1111/epi.17397
Abstract: This study was undertaken to develop consensus‐based recommendations for the management of adult and pediatric patients with new onset refractory status epilepticus (NORSE)/febrile infection‐related epilepsy syndrome (FIRES) based on best evidence and experience. read more here.
Keywords: refractory status; status epilepticus; febrile infection; onset refractory ... See more keywords
Bridging the Gap: Tailoring an Approach to Treatment in Febrile Infection-Related Epilepsy Syndrome.
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DOI: 10.1212/wnl.0000000000207068
Abstract: Cytokine profiling prior to immunotherapy is increasingly prevalent in Febrile infection-related epilepsy syndrome (FIRES). In this case, an 18-year-old boy presented with first-onset seizure after a nonspecific febrile illness. He developed super refractory status epilepticus… read more here.
Keywords: epilepsy syndrome; cytokine; related epilepsy; febrile infection ... See more keywords
Long-term outcomes of adult cryptogenic febrile infection–related epilepsy syndrome (FIRES)
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DOI: 10.3389/fneur.2022.1081388
Abstract: Background Cryptogenic febrile infection-related epilepsy syndrome (FIRES) is a rare but catastrophic encephalopathic condition. We aimed to investigate the long-term outcome in adult cryptogenic FIRES. Methods This was a retrospective study based on the prospective… read more here.
Keywords: long term; cryptogenic febrile; febrile infection; adult cryptogenic ... See more keywords