Articles with "fecd" as a keyword



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Morning myopic shift and glare in advanced Fuchs endothelial corneal dystrophy.

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Published in 2020 at "American journal of ophthalmology"

DOI: 10.1016/j.ajo.2020.01.011

Abstract: PURPOSE Impaired subjective morning visual acuity with improvement of symptoms during the day is pathognomonic for corneal endothelial dysfunction in advanced Fuchs endothelial corneal dystrophy (FECD). This study aimed to analyze the daily fluctuations of… read more here.

Keywords: control group; corneal; fecd; group ... See more keywords
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Fuchs endothelial corneal dystrophy and macular drusen: evidence for coincidence?

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Published in 2018 at "Eye"

DOI: 10.1038/eye.2017.301

Abstract: The corneal endothelium and the retinal pigment epithelium represent monolayers of postmitotic polygonal cells of neuroectodermal origin with barrier and transport function. Fuchs endothelial corneal dystrophy (FECD) and age-related macular degeneration (AMD) show interesting similarities… read more here.

Keywords: corneal; fecd; presence; age ... See more keywords

Association of rs613872 and Trinucleotide Repeat Expansion in the TCF4 Gene of German Patients With Fuchs Endothelial Corneal Dystrophy.

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Published in 2019 at "Cornea"

DOI: 10.1097/ico.0000000000001952

Abstract: PURPOSE To investigate single nucleotide polymorphisms (SNPs) and trinucleotide repeat (TNR) expansion in the transcription factor 4 (TCF4) gene in a large cohort of German patients with Fuchs endothelial corneal dystrophy (FECD). METHODS Genomic DNA… read more here.

Keywords: rs613872; fecd; corneal; trinucleotide repeat ... See more keywords
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Association between Fuchs Endothelial Corneal Dystrophy, Diabetes Mellitus and Multimorbidity

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Published in 2022 at "Cornea"

DOI: 10.1101/2022.12.14.22283472

Abstract: Purpose: To assess risk for demographic variables and other health conditions that are associated with Fuchs endothelial corneal dystrophy (FECD). Methods: We developed a FECD case-control algorithm based on structured EHR data and accuracy confirmed… read more here.

Keywords: fecd; endothelial corneal; fuchs endothelial; risk ... See more keywords
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Global Prevalence of Fuchs Endothelial Corneal Dystrophy (FECD) in Adult Population: A Systematic Review and Meta-Analysis

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Published in 2022 at "Journal of Ophthalmology"

DOI: 10.1155/2022/3091695

Abstract: Purpose To evaluate the global prevalence of Fuchs endothelial corneal dystrophy (FECD). Design Systematic review and meta-analysis. Methods A systematic electronic literature search was conducted on PubMed/MedLine, Cochrane Library, and Google Scholar, in order to… read more here.

Keywords: meta analysis; prevalence; fecd; analysis ... See more keywords
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Comprehensive characterization of DNA methylation changes in Fuchs endothelial corneal dystrophy

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Published in 2017 at "PLoS ONE"

DOI: 10.1371/journal.pone.0175112

Abstract: Transparency of the human cornea is necessary for vision. Fuchs Endothelial Corneal Dystrophy (FECD) is a bilateral, heritable degeneration of the corneal endothelium, and a leading indication for corneal transplantation in developed countries. While the… read more here.

Keywords: corneal; dna methylation; fuchs endothelial; fecd ... See more keywords
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TGC repeat expansion in the TCF4 gene increases the risk of Fuchs’ endothelial corneal dystrophy in Australian cases

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Published in 2017 at "PLoS ONE"

DOI: 10.1371/journal.pone.0183719

Abstract: Fuchs’ endothelial corneal dystrophy (FECD) is a progressive, vision impairing disease. Common single nucleotide polymorphisms (SNPs) and a trinucleotide repeat polymorphism, thymine-guanine-cytosine (TGC), in the TCF4 gene have been associated with the risk of FECD… read more here.

Keywords: fecd; repeat; tgc repeat; tcf4 ... See more keywords