HFD-fed mice appeared more severe spermatogenesis impairment by lead exposure: perspective from gut microbiota and the efficacy of probiotics.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.12309
Abstract: BACKGROUND The mechanism of multifactorial spermatogenesis impairment is unclear. This study aims to investigate the reproductive toxicity of Pb in high-fat diet (HFD)-fed mice, and delineate the important role of gut microbiota. RESULTS Results showed… read more here.
Keywords: hfd fed; spermatogenesis; fed mice; gut microbiota ... See more keywords
Modulation of PPARα-Thermogenesis-Gut Microbiota Interactions in Obese Mice Administrated with Zingerone.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.12352
Abstract: BACKGROUND The present study aimed to uncover the potential effects of zingerone (ZIN), one of the bioactive compounds in ginger, on the development of obesity as well as the mechanisms in C57BL/6J mice fed with… read more here.
Keywords: adipose tissue; ppar; fed mice; gut microbiota ... See more keywords
Banana green peels extract protects against nonalcoholic fatty liver disease in high‐fat‐fed mice through modulation of lipid metabolism and inflammation
Sign Up to like & getrecommendations! Published in 2022 at "Phytotherapy Research"
DOI: 10.1002/ptr.7366
Abstract: We investigate the effect of the banana green peels extract (BPE) as a preventive treatment against NAFLD in high‐fat diet fed mice. Mice received daily doses of 100 or 250 mg/kg of BPE for 12 weeks along… read more here.
Keywords: banana green; green peels; fed mice; peels extract ... See more keywords
Novel 5-HT3 receptor antagonist QCM-4 attenuates depressive-like phenotype associated with obesity in high-fat-diet-fed mice
Sign Up to like & getrecommendations! Published in 2017 at "Psychopharmacology"
DOI: 10.1007/s00213-017-4558-0
Abstract: RationaleDepression associated with obesity remains an interesting area to study the biological mechanisms and novel therapeutic intervention.ObjectivesThe present study investigates the effect of a novel 5-HT3 receptor antagonist 3-methoxy-N-p-tolylquinoxalin-2-carboxamide (QCM-4) on several pathogenic markers of… read more here.
Keywords: hfd fed; fed mice; mice; qcm ... See more keywords
Gelidium amansii ethanol extract suppresses fat accumulation by down-regulating adipogenic transcription factors in ob/ob mice model
Sign Up to like & getrecommendations! Published in 2017 at "Food Science and Biotechnology"
DOI: 10.1007/s10068-017-0028-z
Abstract: The purpose of this study was to determine the anti-obesity effects of Gelidium amansii extract (GAE) in the C57BL/6J-ob/ob mice. The ob/ob mice were fed GAE at 0.5% for 4 weeks, after which body weight,… read more here.
Keywords: accumulation; gae fed; gae; fed mice ... See more keywords
Effect of Kombucha on gut-microbiota in mouse having non-alcoholic fatty liver disease
Sign Up to like & getrecommendations! Published in 2018 at "Food Science and Biotechnology"
DOI: 10.1007/s10068-018-0433-y
Abstract: Non-alcoholic fatty liver disease (NAFLD) is one of the most common liver disorders. Possible links have been recently found between the gut-microbiota and the host metabolism in development of NAFLD and obesity. Therefore, understanding the… read more here.
Keywords: alcoholic fatty; microbiota; non alcoholic; fed mice ... See more keywords
A high-fat diet induced NMRI mouse model of metabolic syndrome: focus on brain-derived neurotrophic factor (BDNF)
Sign Up to like & getrecommendations! Published in 2018 at "Metabolic Brain Disease"
DOI: 10.1007/s11011-018-0271-x
Abstract: The association of brain-derived neurotrophic factor (BDNF) as a member of neurotrophin family and metabolic syndrome (MetS) has been proposed, however basic evidence necessary to prove (or disprove) this association in non-genetic animal model is… read more here.
Keywords: brain derived; fed mice; model; bdnf ... See more keywords
Dihydromyricetin Improves Mitochondrial Biogenesis in the Liver of Alcohol Fed Mice via the AMPK/Sirt-1/PGC-1α Signaling Axis.
Sign Up to like & getrecommendations! Published in 2020 at "Alcohol"
DOI: 10.1016/j.alcohol.2020.10.002
Abstract: Alcoholic liver disease (ALD), due to the multifactorial damage associated with alcohol (ethanol/EtOH) consumption and metabolism, is one of the most prevalent liver diseases in the United States. The liver is the primary site of… read more here.
Keywords: mitochondrial biogenesis; sirt; liver; fed mice ... See more keywords
A Functional Role of GAS6/TAM in Nonalcoholic Steatohepatitis Progression Implicates AXL as Therapeutic Target
Sign Up to like & getrecommendations! Published in 2019 at "Cellular and Molecular Gastroenterology and Hepatology"
DOI: 10.1016/j.jcmgh.2019.10.010
Abstract: Background and Aims GAS6 signaling, through the TAM receptor tyrosine kinases AXL and MERTK, participates in chronic liver pathologies. Here, we addressed GAS6/TAM involvement in Non-Alcoholic SteatoHepatitis (NASH) development. Methods GAS6/TAM signaling was analyzed in… read more here.
Keywords: gas6; gas6 tam; hfd fed; fed mice ... See more keywords
Fermented ginseng, GBCK25, ameliorates steatosis and inflammation in nonalcoholic steatohepatitis model
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Ginseng Research"
DOI: 10.1016/j.jgr.2017.10.002
Abstract: Background Nonalcoholic steatohepatitis (NASH) is one of the chronic inflammatory liver diseases and a leading cause of advanced liver fibrosis, cirrhosis, and hepatocellular carcinoma. The main purpose of this study was to clarify the effects… read more here.
Keywords: nonalcoholic steatohepatitis; gbck25; inflammation; fed mice ... See more keywords
Differential effects of high‐fat diets before pregnancy and/or during pregnancy on fetal growth development
Sign Up to like & getrecommendations! Published in 2018 at "Life Sciences"
DOI: 10.1016/j.lfs.2018.10.008
Abstract: Aims: The aim of the study was to investigate the effects of high‐fat diets before pregnancy and/or during pregnancy on fetal development. Main methods: Female mice were fed with standard diets (SD) or high‐fat diets… read more here.
Keywords: hfd fed; fed mice; high fat; pregnancy ... See more keywords