Positive feedback amplification in swarming immune cell populations.
Sign Up to like & getrecommendations! Published in 2021 at "Current opinion in cell biology"
DOI: 10.1016/j.ceb.2021.07.009
Abstract: Several immune cell types (neutrophils, eosinophils, T cells, and innate-like lymphocytes) display coordinated migration patterns when a population, formed of individually responding cells, moves through inflamed or infected tissues. "Swarming" refers to the process in… read more here.
Keywords: positive feedback; immune cell; feedback amplification; cell ... See more keywords
Proprioceptive feedback amplification restores effective locomotion in a neuromechanical model of lampreys with spinal injuries.
Sign Up to like & getrecommendations! Published in 2023 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2213302120
Abstract: Spinal injuries in many vertebrates can result in partial or complete loss of locomotor ability. While mammals often experience permanent loss, some nonmammals, such as lampreys, can regain swimming function, though the exact mechanism is… read more here.
Keywords: spinal injuries; feedback amplification; proprioceptive feedback; model ... See more keywords
Efficient apoptosis requires feedback amplification of upstream apoptotic signals by effector caspase-3 or -7
Sign Up to like & getrecommendations! Published in 2019 at "Science Advances"
DOI: 10.1126/sciadv.aau9433
Abstract: Caspase-3 and -7 are redundantly required to amplify the extrinsic and intrinsic apoptotic cascade in human leukemia. Apoptosis is a complex multi-step process driven by caspase-dependent proteolytic cleavage cascades. Dysregulation of apoptosis promotes tumorigenesis and… read more here.
Keywords: caspase; apoptosis; upstream apoptotic; feedback amplification ... See more keywords